Maleimide Linkers
The maleimide linkers react specifically with sulfhydryl groups when the pH is between 6.5 and 7.5. The reaction forms a stable thioether linkage. When pH is higher than 8.5, the maleimide linkers readily react with primary amines. Maleimides do not react with tyrosines, histidines or methionines.
AxisPharm provide a broad range of maleimide linkers with various functional groups, such as Mal-PEG-azide, Mal-PEG-alkyne, Mal-PEG-NHS ester, Mal-PEG-TCO, Mal-PEG-BCN, Mal-PEG-DBCO and Mal-PEG-fluorescent dye probes, Mal-PEG-folate and Mal-PEG-biotin, etc.
| Catalog No. | Name | Structure | M.W. | Pricing | |
|---|---|---|---|---|---|
| AP10932 | Mal-propionylamido-PEG2-NHS acetate |
|
411.37 | Pricing | |
| Boc-HyNic-PEG-Mal | |||||
| AP10595 | Boc-HyNic-PEG1-Mal |
|
419.44 | Pricing | |
| Mal-amide-PEG-oxyamine | |||||
| AP10062 | Mal-amide-PEG2-oxyamine |
|
315.32 | Pricing | |
| AP10061 | Mal-amide-PEG3-oxyamine |
|
359.37 | Pricing | |
| AP10059 | Mal-amide-PEG3-oxyamineBoc |
|
459.49 | Pricing | |
| Mal-PEG-oxyamine | |||||
| AP10056 | Mal-PEG2-oxyamine |
|
244.24 | Pricing | |
| AP10058 | Mal-PEG3-oxyamine |
|
288.3 | Pricing | |
| Mal-CH2CyclohexylcarboxylhydrazideTFA | |||||
| AP10045 | Mal-CH2CyclohexylcarboxylhydrazideTFA |
|
348.30 | Pricing | |
| AP10695 | Mal-PEG2-Val-Cit-PAB-OH |
|
618.7 | Pricing | |
| AP10696 | Mal-PEG4-Val-Cit-PAB-OH |
|
706.8 | Pricing | |