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The maleimide linkers react specifically with sulfhydryl groups when the pH is between 6.5 and 7.5. The reaction forms a stable thioether linkage. When pH is higher than 8.5, the maleimide linkers readily react with primary amines. Maleimides do not react with tyrosines, histidines or methionines.

AxisPharm provide a broad range of maleimide linkers with various functional groups, such as Mal-PEG-azide, Mal-PEG-alkyne, Mal-PEG-NHS ester, Mal-PEG-TCO, Mal-PEG-BCN, Mal-PEG-DBCO and Mal-PEG-fluorescent dye probes, Mal-PEG-folate and Mal-PEG-biotin, etc.

Catalog# Name Structure M.W. Purity Pricing
Maleimide Linkers
AP10595Boc-HyNic-PEG1-Mal
Quick viewBoc-HyNic-PEG1-Mal
419.44≥95% Pricing
AP10062Mal-amide-PEG2-oxyamine
Quick viewMal-amide-PEG2-oxyamine
315.32≥95% Pricing
AP10061Mal-amide-PEG3-oxyamine
Quick viewMal-amide-PEG3-oxyamine
359.37≥95% Pricing
AP10059Mal-amide-PEG3-oxyamineBoc
Quick viewMal-amide-PEG3-oxyamineBoc
459.49≥95% Pricing
AP10628APDye 488 Maleimide
Quick viewAPDye 488 Maleimide
684.65≥95% Pricing
AP10739BCN-endo-PEG3-Maleimide
Quick viewBCN-endo-PEG3-Maleimide
519.6≥95% Pricing
AP10738BCN-exo-PEG7-Maleimide
Quick viewBCN-exo-PEG7-Maleimide
739.86≥95% Pricing
AP10593HyNic-PEG1-Mal
Quick viewHyNic-PEG1-Mal
359.39≥95% Pricing
AP11175Mal-NH-ethyl-SS-propionic acid
Quick viewMal-NH-ethyl-SS-propionic acid
332.39≥95% Pricing
AP11188PC Mal-NHS carbonate ester
Quick viewPC Mal-NHS carbonate ester
562.49≥95% Pricing
AP10860DBCO-maleimide
Quick viewDBCO-maleimide
356.38≥95% Pricing
AP10300DBCO-Mal
Quick viewDBCO-Mal
427.45≥95% Pricing
AP10855DBCO-Sulfo-Maleimide
Quick viewDBCO-Sulfo-Maleimide
578.6≥95% Pricing
AP10313DBCO-NH-PEG2-Mal
Quick viewDBCO-NH-PEG2-Mal
586.64≥95% Pricing
AP10858DBCO-amido-PEG4-amido-Maleimide
Quick viewDBCO-amido-PEG4-amido-Maleimide
674.75≥95% Pricing
AP10315DBCO-NH-PEG6-Mal
Quick viewDBCO-NH-PEG6-Mal
762.85≥95% Pricing
AP10856DBCO-Sulfo-PEG4-Maleimide
Quick viewDBCO-Sulfo-PEG4-Maleimide
825.89≥95% Pricing
AP10316DBCO-NH-PEG12-Mal
Quick viewDBCO-NH-PEG12-Mal
1027.16≥95% Pricing
AP10158m-PEG2-Mal
Quick viewm-PEG2-Mal
199.21≥95% Pricing
AP11362m-PEG4-Mal
Quick viewm-PEG4-Mal
358.39≥95% Pricing
AP10186m-PEG6-NH-Mal
Quick viewm-PEG6-NH-Mal
446.49≥95% Pricing
AP10187m-PEG8-NH-Mal
Quick viewm-PEG8-NH-Mal
534.6≥95% Pricing
AP11363m-PEG12-Mal
Quick viewm-PEG12-Mal
710.82≥95% Pricing
AP11364m-PEG24-Mal
Quick viewm-PEG24-Mal
1239.45≥95% Pricing
AP11365m-PEG36-Mal
Quick viewm-PEG36-Mal
1768.09≥95% Pricing