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Biotin PEG linkers combine biotin with PEG to boost solubility, stability, and bioavailability. They easily conjugate to proteins, peptides, and biomolecules. This makes them useful in drug delivery, diagnostics, and research. Biotin PEG linkers also enhance pharmacokinetics and targeting. These features make them essential tools in biochemistry and molecular biology.

Cat# Name Structure M.W. Purity Pricing
BCN-PEG-Biotin
AP15258exo BCN Biotin376.52≥95% Pricing
AP10754endo-BCN-PEG2-Biotin550.71≥95% Pricing
AP13123BCN-PEG2-Biotin550.71≥95% Pricing
AP10697endo-BCN-PEG3-Biotin594.77≥95% Pricing
AP13124BCN-PEG3-Biotin594.77≥95% Pricing
Biotin acid PEG
AP10513Biotin-PEG2-acid403.50≥95% Pricing
AP10514Biotin-PEG3-acid447.55≥95% Pricing
AP15481Biotin C3 acid329.42≥95% Pricing
AP10515Biotin-PEG4-acid491.60≥95% Pricing
AP10516Biotin-PEG6-acid579.71≥95% Pricing
AP10517Biotin-PEG8-acid667.81≥95% Pricing
AP10518Biotin-PEG9-acid711.87≥95% Pricing
AP10519Biotin-PEG12-acid844.02≥95% Pricing
AP10520Biotin-PEG24-acid1372.65≥95% Pricing
AP11030Biotin-PEG36-acid1901.3≥95% Pricing
Biotin alcohol PEG
AP10500Biotin-PEG2-alcohol331.43≥95% Pricing
AP10501Biotin-PEG3-alcohol375.49≥95% Pricing
AP10502Biotin-PEG4-alcohol419.54≥95% Pricing
AP13556Biotin-PEG5-alcohol463.6≥95% Pricing
AP10503Biotin-PEG6-alcohol507.64≥95% Pricing
AP10504Biotin-PEG8-alcohol595.75≥95% Pricing
AP10505Biotin-PEG10-alcohol683.85≥95% Pricing
AP10506Biotin-PEG12-alcohol771.96≥95% Pricing
Biotin aldehyde PEG
AP10076Biotin-PEG2-CH2-aldehyde373.47≥95% Pricing
AP10078Biotin-PEG2-aldehyde387.50≥95% Pricing
Biotin alkyne PEG
AP15239Biotin-PEG2-alkyne369.48≥95% Pricing
AP12586Desthiobiotin Alkyne427.54≥95% Pricing
AP11056Biotin-PEG4-alkyne457.59≥95% Pricing
AP11055Biotin-PEG2-C4-alkyne468.61≥95% Pricing
AP11057Biotin-Alkyne528.67≥95% Pricing
AP11060N-(Propargyl-PEG4)-biocytin614.76≥95% Pricing
AP11058Dde Biotin-PEG4-alkyne650.83≥95% Pricing
AP11063UV Cleavable Biotin-PEG2-alkyne736.88≥95% Pricing
AP11061PC Biotin-PEG3-alkyne780.89≥95% Pricing
AP11059Diazo Biotin-PEG3-alkyne795.95≥95% Pricing
AP11064DADPS Biotin Alkyne827.12≥95% Pricing
AP11062PC-Biotin-PEG4-PEG4-alkyne927.08≥95% Pricing
Biotin DBCO PEG
AP10321DBCO-NH-PEG2-Biotin661.81≥95% Pricing
AP10322DBCO-NH-PEG4-Biotin749.92≥95% Pricing
AP10323DBCO-NH-PEG6-Biotin838.02≥95% Pricing
AP11070Dde Biotin-PEG4-DBCO872.09≥95% Pricing
AP15500DBCO-SS-PEG4-Biotin913.18≥95% Pricing
AP13177Biotin-PEG8-DBCO 926.1≥98% Pricing
AP11067Diazo Biotin-PEG3-DBCO973.16≥95% Pricing
AP10324DBCO-NH-PEG12-Biotin1102.34≥95% Pricing
Biotin EDA PFP PEG
AP11075Biotin-EDA-PEG4-PFP728.73≥95% Pricing
Biotin iodide PEG
AP11079Biotin-PEG2-iodide542.43≥95% Pricing
Biotin NHBoc PEG
AP11072Biotin-PEG2-NH-Boc474.62≥95% Pricing
AP13882Biotin-PEG3-NHBoc518.7≥95% Pricing
AP11073Biotin-PEG5-NH-Boc606.78≥95% Pricing
AP13555Biotin-PEG6-NH-Boc650.8≥98% Pricing
Biotin oxyamine PEG
AP11076Biotin-PEG3-oxyamine HCl salt434.55≥95% Pricing
AP11077Biotin-PEG11-oxyamine HCl salt786.98≥95% Pricing
Biotin PFP PEG
AP11040Biotin-PFP ester410.36≥95% Pricing
AP11039Biotin-PEG36-PFP ester2067.35≥95% Pricing
Biotin t-butyl ester PEG
AP13883Biotin-PEG3-t-butyl ester503.7≥95% Pricing
AP11074Biotin-PEG6-t-butyl ester635.81≥95% Pricing
Biotin Tetrazine PEG
AP15161Tetrazine-SS-Biotin 576.77≥95% Pricing
AP11078Biotin-PEG4-methyltetrazine589.71≥95% Pricing
AP14701Biotin-PEG4-amido-methyltetrazine674.8≥95% Pricing
Biotin TFP PEG
AP11036Biotin-PEG4-TFP ester639.66≥95% Pricing
AP11037Biotin-PEG12-TFP ester992.08≥95% Pricing
AP11038Biotin-PEG24-TFP ester1520.72≥95% Pricing
Biotin thiourea PEG
AP11081Biotin-PEG7-thiourea653.85≥95% Pricing
Biotin-EDA-PEG-NHS
AP13619Biotin-EDA-PEG5-NHS703.8≥98% Pricing
Biotin-LC
AP10491Biotin-LC357.47≥95% Pricing
AP10492Biotin-LC-NHS Ester454.54≥95% Pricing
AP10493Biotin-LC-LC470.63≥95% Pricing
AP13884Sulfo-NHS-LC-Biotin534.6≥98% Pricing
AP10494Biotin-LC-LC-NHS Ester567.70≥95% Pricing
Biotin-NHS Ester
AP12608Desthiobiotin NHS Ester311.34≥95% Pricing
AP10489Biotin-NHS Ester341.38≥95% Pricing
AP10492Biotin-LC-NHS Ester454.54≥95% Pricing
AP10496Biotin-SLC-NHS Ester524.68≥95% Pricing
AP10494Biotin-LC-LC-NHS Ester567.70≥95% Pricing
Biotin-PEG-Amide
AP14700Biotin-PEG4-Amide490.60≥95% Pricing
Biotin-PEG-amine
AP10507Biotin-amine286.40≥95% Pricing
AP10508Biotin-PEG2-amine374.50≥95% Pricing
AP10509Biotin-PEG3-amine418.55≥95% Pricing
AP11035Biotin-PEG3-(CH2)3-amine TFA salt446.61≥95% Pricing
AP10510Biotin-PEG4-amine462.61≥95% Pricing
AP11031Biotin-PEG5-amine506.66≥95% Pricing
AP130094-Azidobenzoylamino-PEG2-Biotin519.62≥95% Pricing
AP10511Biotin-PEG6-amine550.71≥95% Pricing
AP11032Biotin-PEG7-amine594.77≥95% Pricing
AP11033Biotin-PEG8-amine638.82≥95% Pricing
AP10676DMTR-biotin-PEG2-amine676.87≥95% Pricing
AP10512Biotin-PEG11-amine770.97≥95% Pricing
AP11034Biotin-PEG23-amine1299.61≥95% Pricing
Biotin-PEG-Azide
AP10534Biotin-PEG2-Azide400.50≥95% Pricing
AP11042Biotin-PEG2-azide400.5≥95% Pricing
AP12584Desthiobiotin Azide414.5≥95% Pricing
AP10535Biotin-PEG3-Azide444.55≥95% Pricing
AP10536Biotin-PEG4-Azide488.60≥95% Pricing
AP11045Biotin-PEG2-C6-azide513.66≥95% Pricing
AP10537Biotin-PEG5-Azide532.66≥95% Pricing
AP11043Biotin-PEG6-azide576.71≥95% Pricing
AP12675Biotin Azide Plus582.72≥95% Pricing
AP11046Biotin-Azide615.79≥95% Pricing
AP11044Biotin-PEG7-azide620.76≥95% Pricing
AP12603Biotin Picolyl Azide622.74≥95% Pricing
AP11047Biotin-PEG4-Picolyl azide622.74≥95% Pricing
AP11051N-(Azido-PEG4)-biocytin645.77≥95% Pricing
AP13554Biotin-PEG8-azide664.8≥98% Pricing
AP12592Dde Biotin Azide695.88≥95% Pricing
AP11048Dde Biotin-PEG4-azide695.88≥95% Pricing
AP11050Diazo Biotin-PEG3-azide711.84≥95% Pricing
AP11053UV Cleavable Biotin-PEG2-Azide781.93≥95% Pricing
AP10538Biotin-PEG11-Azide796.97≥95% Pricing
AP11049Dde Biotin-PEG4-Picolyl azide815.99≥95% Pricing
AP11052PC Biotin-PEG3-azide825.94≥95% Pricing
AP12676Dde Biotin Azide Plus834.05≥95% Pricing
AP11054DADPS Biotin Azide886.19≥95% Pricing
AP12614Fluorescein Biotin Azide1138.23≥95% Pricing
AP10539Biotin-PEG23-Azide1325.62≥95% Pricing
Biotin-PEG-Hydrazide
AP10490Biotin-Hydrazide258.34≥95% Pricing
AP10497Biotin-LC-Hydrazide371.50≥95% Pricing
AP10529Biotin-PEG2-Hydrazide417.53≥95% Pricing
AP10530Biotin-PEG3-Hydrazide461.58≥95% Pricing
AP10531Biotin-PEG4-Hydrazide505.63≥95% Pricing
AP10532Biotin-PEG6-Hydrazide593.74≥95% Pricing
AP10533Biotin-PEG12-Hydrazide858.05≥95% Pricing
Biotin-PEG-Mal
AP13429Biotin-X-maleimide479.60≥95% Pricing
AP10540Biotin-PEG2-NH-Mal525.62≥95% Pricing
AP10541Biotin-PEG3-NH-Mal569.67≥95% Pricing
AP13266Mal-Cyclohexyl-PEG3-Biotin637.8≥95% Pricing
AP10542Biotin-PEG6-NH-Mal701.83≥95% Pricing
AP11041Biotin-PEG11-NH-Mal922.1≥95% Pricing
AP10543Biotin-PEG12-NH-Mal966.14≥95% Pricing
Bis-Biotin-PEG
AP11065Bis-Biotin-PEG231525.91≥95% Pricing
Branched Biotin PEG
AP14715N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-TFP ester1071.20≥95% Pricing
AP11090N-(Biotin)-N-bis(PEG1-alcohol)419.54≥95% Pricing
AP110922-(Biotin-amido)-1,3-bis(carboxylethoxy)propane461.53≥95% Pricing
AP11093N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester706.85≥95% Pricing
AP11096N-Desthiobiotin-N-bis(PEG4-t-butyl ester)822.05≥95% Pricing
AP11095N-Desthiobiotin-N-bis(PEG4-NHS ester)903.98≥95% Pricing
AP14713N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-acid923.10≥95% Pricing
AP11091N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt959.16≥95% Pricing
AP13420N-(DBCO-PEG4)-N-Biotin-PEG4-acid998.2≥98% Pricing
AP14714N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-NHS1020.20≥95% Pricing
AP13419N-(acid-PEG3)-N-bis(PEG3-biotin)1024.3≥98% Pricing
AP11727N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)1071.37≥95% Pricing
AP11094N-(DBCO-PEG4)-N-Biotin-PEG4-NHS1095.27≥95% Pricing
AP13586N-(DBCO-PEG4)-N-Biotin-PEG4-hydrazide TFA salt1112.2≥85% Pricing
AP13584N-(Fmoc-N-amido-PEG4)-N-Biotin-PEG4-t-Boc-Hydrazide1112.4≥98% Pricing
AP13581N-(triethoxysilane-PEG36-PEG3-)-N-bis(PEG3-biotin) 2884.7≥98% Pricing
Cleavable Biotin
AP13155Desthiobiotin-PEG3-Amine388.50≥95% Pricing
AP11082Azide-SS-biotin404.57≥95% Pricing
AP13585Biotin-SS-Amine HCl Salt415≥98% Pricing
AP14850Biotin-cystamine hydrochloride415.05≥95% Pricing
AP14138Biotin-HPDP539.80≥95% Pricing
AP11058Dde Biotin-PEG4-alkyne650.83≥95% Pricing
AP11083Biotin-PEG3-SS-azide692.91≥95% Pricing
AP11048Dde Biotin-PEG4-azide695.88≥95% Pricing
AP11050Diazo Biotin-PEG3-azide711.84≥95% Pricing
AP14079Biotin Gly-Gly-Gly768.90≥95% Pricing
AP11061PC Biotin-PEG3-alkyne780.89≥95% Pricing
AP11053UV Cleavable Biotin-PEG2-Azide781.93≥95% Pricing
AP11059Diazo Biotin-PEG3-alkyne795.95≥95% Pricing
AP11086PC-Biotin-PEG4-NHS carbonate810.87≥95% Pricing
AP11049Dde Biotin-PEG4-Picolyl azide815.99≥95% Pricing
AP11085PC Biotin-PEG3-NHS carbonate ester840.9≥95% Pricing
AP15500DBCO-SS-PEG4-Biotin913.18≥95% Pricing
AP11084PC-Biotin-PEG4-PEG3-azide914.04≥95% Pricing
AP11062PC-Biotin-PEG4-PEG4-alkyne927.08≥95% Pricing
AP12701PC DBCO-NHS Ester945.98≥95% Pricing
AP11067Diazo Biotin-PEG3-DBCO973.16≥95% Pricing
D-Biotin Thalidomide PEG
AP11080D-Biotin-PEG6-Thalidomide791.91≥95% Pricing
DBCO-Biotin & DBCO-PEG-Biotin
AP10303DBCO-Biotin502.63≥95% Pricing
AP11066DBCO-Sulfo-Link-biotin653.77≥95% Pricing
AP10321DBCO-NH-PEG2-Biotin661.81≥95% Pricing
AP12585Desthiobiotin-PEG4-DBCO719.87≥95% Pricing
AP11069DBCO-PEG4-Desthiobiotin719.88≥95% Pricing
AP10322DBCO-NH-PEG4-Biotin749.92≥95% Pricing
AP10323DBCO-NH-PEG6-Biotin838.02≥95% Pricing
AP13177Biotin-PEG8-DBCO 926.1≥98% Pricing
AP10324DBCO-NH-PEG12-Biotin1102.34≥95% Pricing
Diketone-PEG-Biotin
AP11310Diketone-PEG4-Biotin678.84≥95% Pricing
AP11311Diketone-PEG12-Biotin1031.27≥95% Pricing
Disulfide Linkers
AP11154Aminoethyl-SS-ethylamine152.27≥95% Pricing
AP11151Aminoethyl-SS-ethylalcohol153.26≥95% Pricing
AP11158Azidoethyl-SS-ethylamine178.27≥95% Pricing
AP11005Azidoethyl-SS-ethylalcohol179.26≥95% Pricing
AP11152Aminoethyl-SS-propionic acid181.27≥95% Pricing
AP13848Disulfide Azide Agarose188.28≥95% Pricing
AP11156Azidoethyl-SS-propionic acid207.27≥95% Pricing
AP11001Azido-SS-PEG2-acid295.37≥95% Pricing
AP11157Azidoethyl-SS-propionic NHS ester304.34≥95% Pricing
AP111812-hydroxyethyl disulfide mono-Tosylate308.43≥95% Pricing
AP137213-[[2-[(4-azidobenzoyl)amino]ethyl]dithio]propanoicacid 326.4≥96% Pricing
AP13833NHS-PEG1-SS-PEG1-NHS436.4≥95% Pricing
AP135514-Azide-TFP-Amide-PEG4-acid482.4≥98% Pricing
AP11184NThiol-SS-biotin504.64≥95% Pricing
AP11183Biotin-bisamido-SS-NHS575.71≥95% Pricing
AP11185Sulfo-NThiol-SS-biotin606.67≥95% Pricing
AP13847Disulfide Biotin Alkyne647.87≥95% Pricing
AP13846Disulfide Biotin Azide692.91≥95% Pricing
AP11153Amino-SS-PEG12-acid709.9≥95% Pricing
AP13845Disulfide Biotin DBCO869.12≥95% Pricing
Fmoc-Asp(biotinyl-PEG)-OH
AP15269Fmoc-Asp(biotinyl-PEG)-OH783.94≥95% Pricing
Fmoc-Glu(biotinyl-PEG)-OH
AP15270Fmoc-Glu(biotinyl-PEG)-OH797.97≥95% Pricing
Fmoc-Lys (biotin-PEG)-OH
AP11087Fmoc-Lys (biotin-PEG4)-OH842.02≥95% Pricing
AP11088Fmoc-Lys (biotin-PEG12)-OH1194.44≥95% Pricing
AP15278Fmoc-D-Lys-(biotin-PEG12)-OH1194.44≥95% Pricing
Iodo-PEG-Biotin
AP13571Iodoacetyl-LC-Biotin510.4≥97% Pricing
Norbornene-PEG-Biotin
AP10574Norbornene-PEG1 Biotin450.60≥95% Pricing
AP10575Norbornene-PEG2 Biotin494.65≥95% Pricing
AP10573Norbornene-PEG3 Biotin538.70≥95% Pricing
AP10580Norbornene-PEG11 Biotin891.12≥95% Pricing
Other Biotin Linkers
AP10673Biotinyl tyramide363.48≥95% Pricing
AP10499Biotin-ONP365.41≥95% Pricing
AP14683Biocytin hydrochloride372.48≥95% Pricing
AP14706Biocytin372.50≥95% Pricing
AP10498Biotin-NH-CH2CH2-S-S-Pyr412.60≥95% Pricing
AP10495Biotin-SLC427.60≥95% Pricing
AP14559N-Boc-Biocytin472.60≥95% Pricing
AP15569Biotin-PEG-Thiol479.65≥95% Pricing
AP14707Bioymifi 494.32≥95% Pricing
AP10675DMT-Biotin546.68≥95% Pricing
AP13057Biotin-PEG3-trifluoromethyl-diazirinyl-benzoic acid603.61≥95% Pricing
AP12649Biotin-PEG4-STP Ester719.72≥90% Pricing
AP10674DMT-Biotin-C6 Phosphoramidite847.06≥95% Pricing
AP10672DMTR-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite878.07≥95% Pricing
PEG-Biotin-PEG
AP11726N-(Azido-PEG2)-N-Biotin-PEG3-acid604.72≥95% Pricing
AP11093N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester706.85≥95% Pricing
AP11732N-(Amino-PEG4)-N-Biotin-PEG4-acid710.88≥95% Pricing
AP11731N-Biotin-N,N-bis(PEG4-acid)739.88≥95% Pricing
AP11096N-Desthiobiotin-N-bis(PEG4-t-butyl ester)822.05≥95% Pricing
AP11095N-Desthiobiotin-N-bis(PEG4-NHS ester)903.98≥95% Pricing
AP11094N-(DBCO-PEG4)-N-Biotin-PEG4-NHS1095.27≥95% Pricing
Photocleavable Biotin
AP13832PC-Biotin-PEG4669.8≥95% Pricing
AP11052PC Biotin-PEG3-azide825.94≥95% Pricing
AP12610PC Biotin-NHS ester840.89≥90% Pricing
AP11062PC-Biotin-PEG4-PEG4-alkyne927.08≥95% Pricing
TCO-PEG-biotin
AP10836TCO-PEG1-Biotin482.64≥95% Pricing
AP10837TCO-PEG2-Biotin526.69≥95% Pricing
AP10838TCO-PEG3-Biotin570.74≥95% Pricing
AP11867TCO-PEG4-biotin614.8≥95% Pricing
AP10839TCO-PEG5-Biotin658.85≥95% Pricing
AP14141TCO-PEG8-Biotin791.00≥95% Pricing
AP14142TCO-PEG12-Biotin967.20≥95% Pricing
Tetrazine-PEG-Biotin
AP11078Biotin-PEG4-methyltetrazine589.71≥95% Pricing
AP15162Tetrazine-PEG4-biotin660.78≥95% Pricing
AP14701Biotin-PEG4-amido-methyltetrazine674.8≥95% Pricing

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    Biotin PEG Linkers: Essential Tools for Accurate Purification and Detection

    Biotin PEG linkers are invaluable in molecular biology and biochemistry for non-radioactive purification, detection, immobilization, labeling, and targeting. Combining the high affinity of biotin (vitamin H) with the solubility benefits of polyethylene glycol (PEG), these linkers form highly stable complexes with avidin and streptavidin, even under extreme conditions like varying pH, temperature, and organic solvents. Why Choose Biotin PEG Linkers from AxisPharm?
    • Versatility: Our biotinylation reagents feature a range of functional groups, catering to diverse research applications.
    • Enhanced Solubility: The PEG spacer improves solubility, reducing toxic or immunological effects for more reliable results.
    • Precise Control: Mono-dispersed PEG linkers allow precise control over spacer length, optimizing performance in biotin-binding assays with streptavidin, avidin, and other avidin proteins.
    Key Features:
    • Strong Binding Affinity: Rapid and specific interaction with avidin and streptavidin ensures stable complex formation.
    • Stable Complexes: Maintains stability under extreme conditions, including changes in pH, temperature, and solvents.
    Applications:
    • Purification: Non-radioactive purification of biomolecules.
    • Detection: Enhanced sensitivity and specificity in detection assays.
    • Immobilization: Effective immobilization of biotinylated molecules for various applications.
    • Labeling: Precise protein biotinylation labeling for tracking and analysis.
    • Targeting: Specific targeting in biological assays and experiments.
    Choosing the right biotinylation reagent involves considering solubility, spacer length, reversibility, and functional group compatibility. AxisPharm provides a comprehensive range of biotin PEG linkers, ensuring you find the perfect solution for your research needs. Ref: Chaturvedi R, Kang Y, Eom Y, Torati SR, Kim C. Functionalization of Biotinylated Polyethylene Glycol on Live Magnetotactic Bacteria Carriers for Improved Stealth Properties. Biology (Basel). 2021 Oct 1;10(10):993. Universal Biotin–PEG-Linked Gold Nanoparticle Probes for the Simultaneous Detection of Nucleic Acids and Proteins Alexander W. Scott, Viswanadham Garimella, Colin M. Calabrese, and Chad A. Mirkin Bioconjugate Chemistry 2017 28 (1), 203-211

    Ultimate Guide to Choosing the Right Biotin PEG Linker