Cleavable peptides are a type of peptide molecule that contain specific chemical bonds that can be broken down under certain conditions. These peptides are widely used in a variety of applications, including drug discovery, proteomics, and bioconjugation. Cleavable peptides can be divided into two broad categories: enzymatically cleavable peptides and chemically cleavable peptides.
Enzymatically cleavable peptides are those that contain specific amino acid sequences that can be cleaved by certain enzymes. These enzymes are often found in biological systems and can be used to trigger the release of the peptide or attached cargo molecule. Enzymatically cleavable peptides are commonly used in drug delivery applications, where they can be used to target specific cells or tissues and release the drug payload only in the desired location.
