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PEG NHS ester linkers have been widely usded for crosslinking or labeling peptides and proteins. They readily react with primary amine groups at the N-terminus of polypeptide chains and lysine amino groups. These primary amines exist predominantly on the outside surfaces of protein and are readily accessible to NHS ester for bioconjugations. In addition, these primary amines are nucleophilic enough to react with PEG-NHS esters for protein crosslinking and labeling.

The functional groups on the other end of the linkers provide protein scientist opportunities for further conjugation with other biomolecules or drug targets.

Incorporating a PEG spacer can dramatically improve the solubility of the linker and make them ideal for ADC conjugations as most of the process take place in aqueous media.

AxisPharm maintain a large collection of high quality PEG NHS ester linkers for our clients to select. For custom synthesis of ADC linkers, please contact us. 

Cat# Name Structure M.W. Purity Pricing
(2-pyridyldithio)-PEG-NHS ester
AP10769(2-pyridyldithio)-PEG4-NHS ester488.58≥95% Pricing
Acid-PEG-NHS ester
AP10913Acid-PEG2-NHS ester303.27≥95% Pricing
AP11823Acid-PEG3-NHS ester347.32≥95% Pricing
AP13397Acid-PEG4-NHS ester391.4≥97% Pricing
AP11824Acid-PEG5-NHS ester435.43≥95% Pricing
AP11825Acid-PEG9-NHS ester611.64≥95% Pricing
AP11826Acid-PEG13-NHS ester787.85≥95% Pricing
AP11827Acid-PEG25-NHS ester1316.49≥95% Pricing
ald-benzoylamide-PEG-CH2 NHS ester
AP10068Ald-benzoylamide-PEG2-CH2 NHS ester392.36≥95% Pricing
AP10066Ald-benzoylamide-PEG3-CH2 NHS ester436.41≥95% Pricing
AP10064Ald-benzoylamide-PEG4-CH2 NHS ester480.47≥95% Pricing
Ald-PEG-NHS ester
AP12243Ald-Ph-PEG2-NHS406.39≥95% Pricing
AP12244Ald-Ph-PEG4-NHS ester494.5≥95% Pricing
AP12245Ald-Ph-PEG24-NHS ester1375.56≥95% Pricing
Azido-PEG-aminoacetic acid-NHS ester
AP11534Azido-PEG3-aminoacetic acid-NHS ester373.36≥95% Pricing
Azido-PEG-CH2CO2-NHS
AP11528Azido-PEG1-CH2CO2-NHS242.19≥95% Pricing
AP11529Azido-PEG2-CH2CO2-NHS286.24≥95% Pricing
AP11530Azido-PEG3-CH2CO2-NHS330.29≥95% Pricing
AP11531Azido-PEG4-CH2CO2-NHS374.35≥95% Pricing
AP11532Azido-PEG5-CH2CO2-NHS418.40≥95% Pricing
AP11533Azido-PEG8-CH2CO2-NHS550.56≥95% Pricing
Azido-PEG-NHS ester
AP11522Azidoacetic acid NHS ester198.14≥95% Pricing
AP11523Azido-PEG1-NHS ester256.22≥95% Pricing
AP11524Azido-PEG2-NHS ester300.27≥95% Pricing
AP10258Azido-PEG3-NHS ester344.32≥95% Pricing
AP10259Azido-PEG4-NHS ester388.37≥95% Pricing
AP11525Azido-PEG5-NHS ester432.43≥95% Pricing
AP10260Azido-PEG6-NHS ester476.48≥95% Pricing
AP13240Azido-PEG7-NHS ester520.5≥95% Pricing
AP10261Azido-PEG8-NHS ester564.58≥95% Pricing
AP11526Azido-PEG9-NHS ester608.64≥95% Pricing
AP11527Azido-PEG10-NHS ester652.7≥95% Pricing
AP10262Azido-PEG12-NHS ester740.79≥95% Pricing
AP10263Azido-PEG16-NHS ester917.01≥95% Pricing
AP10264Azido-PEG24-NHS ester1269.43≥95% Pricing
Azido-PEG-succinimidyl carbonate
AP10095Azido-peg3-succinimidyl carbonate360.32≥95% Pricing
AP10094Azido-PEG5-succinimidyl carbonate448.43≥95% Pricing
Benzyloxy carbonyl-PEG-NHS ester
AP11672Benzyloxy carbonyl-PEG3-NHS ester437.45≥95% Pricing
AP13374Benzyloxy carbonyl-PEG4-NHS ester481.5≥98% Pricing
Biotin-NHS Ester
AP12608Desthiobiotin NHS Ester311.34≥95% Pricing
AP10489Biotin-NHS Ester341.38≥95% Pricing
AP10492Biotin-LC-NHS Ester454.54≥95% Pricing
AP10496Biotin-SLC-NHS Ester524.68≥95% Pricing
AP10494Biotin-LC-LC-NHS Ester567.70≥95% Pricing
Biotin-PEG-NHS Ester
AP10521Biotin-PEG2-NHS Ester500.57≥95% Pricing
AP10522Biotin-PEG3-NHS Ester544.62≥95% Pricing
AP10523Biotin-PEG4-NHS Ester588.67≥95% Pricing
AP10524Biotin-PEG6-NHS Ester676.78≥95% Pricing
AP10525Biotin-PEG8-NHS Ester764.88≥95% Pricing
AP10526Biotin-PEG9-NHS Ester808.93≥95% Pricing
AP10527Biotin-PEG12-NHS Ester941.09≥95% Pricing
AP10528Biotin-PEG24-NHS Ester1469.72≥95% Pricing
AP13375Desthiobiotin-PEG3-NHS ester514.6≥98% Pricing
Bis-aliphatic-NHS ester
AP11958DSG Crosslinker326.26≥95% Pricing
AP11959DSS Crosslinker368.34≥95% Pricing
Bis-PEG-NHS
AP11502Bis-PEG1-NHS ester356.29≥95% Pricing
AP10914Bis-PEG2-NHS ester400.34≥95% Pricing
AP11503Bis-PEG3-NHS ester444.39≥95% Pricing
AP11504Bis-PEG4-NHS ester488.44≥95% Pricing
AP11505Bis-PEG5-NHS ester532.50≥95% Pricing
AP11506Bis-PEG6-NHS ester576.55≥95% Pricing
AP11507Bis-PEG7-NHS ester620.60≥95% Pricing
AP13376Bis-PEG8-NHS ester664.7≥98% Pricing
AP11508Bis-PEG9-NHS ester708.71≥95% Pricing
AP11509Bis-PEG10-NHS ester752.76≥95% Pricing
AP11510Bis-PEG11-NHS ester796.82≥95% Pricing
AP13382Bis-PEG12-NHS ester840.9≥97% Pricing
AP11511Bis-PEG13-NHS ester884.92≥95% Pricing
AP11512Bis-PEG17-NHS ester1061.13≥95% Pricing
AP13377Bis-PEG18-NHS ester1105.2≥98% Pricing
AP11513Bis-PE21-NHS ester1237.34≥95% Pricing
AP11514Bis-PEG25-NHS ester1413.55≥95% Pricing
Branched PEG NHS ester
AP11702N-(Azido-PEG2)-N-Boc-PEG3-NHS ester575.62≥95% Pricing
AP11703N-(Azido-PEG2)-N-Boc-PEG4-NHS ester619.67≥95% Pricing
AP11704N-(Azido-PEG3)-N-Boc-PEG3-NHS ester619.67≥95% Pricing
AP117002-(Azido-PEG3-amido)-1,3-bis(NHS Ester)658.62≥95% Pricing
AP11705N-(Azido-PEG3)-N-Boc-PEG4-NHS ester663.72≥95% Pricing
AP11747N-Mal-N-bis(PEG2-NHS ester)682.64≥95% Pricing
AP11750N-Boc-N-bis(PEG3-NHS ester)719.74≥95% Pricing
AP11699N-NHS-PEG3-N-bisPEG3-azide720.78≥95% Pricing
AP11751N-Boc-N-bis(PEG4-NHS ester)807.84≥95% Pricing
AP11749N-DBCO-N-bis(PEG2-NHS ester)818.83≥95% Pricing
AP11096N-Desthiobiotin-N-bis(PEG4-t-butyl ester)822.05≥95% Pricing
AP11748N-Mal-N-bis(PEG4-NHS ester)858.85≥95% Pricing
AP11095N-Desthiobiotin-N-bis(PEG4-NHS ester)903.98≥95% Pricing
AP11701N-(Azido-PEG4)-N-bis(PEG4-NHS ester)981.02≥95% Pricing
AP13284N-(NHS ester-PEG3)-N-bis(PEG3-Mal) 999≥95% Pricing
AP11094N-(DBCO-PEG4)-N-Biotin-PEG4-NHS1095.27≥95% Pricing
AP11752NThiol-PEG4-(m-PEG4)3-ester1363.55≥95% Pricing
AP11753NThiol-PEG4-(m-PEG12)3-ester2420.83≥95% Pricing
AP13229N-(TCO)-N-bis(PEG4-NHS ester)859.9≥98% Pricing
AP13415Methyltetrazine-amido-N-bis(PEG4-NHS ester) 919.9≥98% Pricing
AP13378DBCO-N-bis(PEG4-NHS ester)995.1≥95% Pricing
AP13286N-(Mal-PEG4)-N-Fluorescein-PEG4-NHS ester1122.2≥96% Pricing
Bromoacetamido-PEG-NHS ester
AP120163-(2-bromoacetamido)propanoic acid NHS ester307.1≥95% Pricing
AP12017Bromoacetamido-PEG2-NHS ester395.21≥95% Pricing
AP10955Bromoacetamido-PEG4-NHS483.31≥95% Pricing
Chloroacetamido-PEG-NHS ester
AP12029Chloroacetamido-PEG4-NHS ester438.86≥95% Pricing
DNP-PEG-CH2 NHS ester
AP10121DNP-PEG3-CH2 NHS ester470.39≥95% Pricing
AP10117DNP-PEG4-CH2 NHS ester514.44≥95% Pricing
DNP-PEG-NHS ester
AP12230DNP-PEG4-NHS ester528.47≥95% Pricing
AP12231DNP-PEG12-NHS ester880.9≥95% Pricing
Fmoc-aminooxy-PEG-NHS ester
AP12088Fmoc-aminooxy-PEG12-NHS ester953.05≥95% Pricing
Fmoc-NMe-PEG-NHS ester
AP11107Fmoc-NMe-PEG4-NHS ester598.65≥95% Pricing
Fmoc-PEG-CH2CO2-NHS
AP10915FmocNH-PEG2-CH2CO2-NHS ester482.48≥95% Pricing
AP10916FmocNH-PEG3-CH2CO2-NHS ester526.54≥95% Pricing
AP10917FmocNH-PEG5-CH2CO2-NHS ester614.64≥95% Pricing
Fmoc-PEG-NHS ester
AP11100Fmoc-PEG1-NHS ester452.46≥95% Pricing
AP10727Fmoc-PEG2-NHS ester496.51≥95% Pricing
AP11101Fmoc-PEG3-NHS ester540.57≥95% Pricing
AP11102Fmoc-PEG4-NHS ester584.62≥95% Pricing
AP11103Fmoc-PEG5-NHS ester628.68≥95% Pricing
AP11104Fmoc-PEG6-NHS ester672.73≥95% Pricing
AP10355Fmoc-PEG8-NHS ester760.83≥95% Pricing
AP11105Fmoc-PEG12-NHS ester937.05≥95% Pricing
AP11106Fmoc-PEG24-NHS ester1465.68≥95% Pricing
Folate-PEG-NHS ester
AP10011Folate PEG3 NHS ester741.71≥95% Pricing
HyNic-PEG-NHS ester
AP10135HyNic NHS ester290.28≥95% Pricing
Lipoamide-PEG-NHS
AP11412alpha-lipoic acid-NHS303.39≥95% Pricing
M-PEG-NHS ester
AP11331m-PEG1-NHS ester201.18≥95% Pricing
AP13398m-PEG2-NHS ester245.2≥98% Pricing
AP10183m-PEG3-NHS Ester289.28≥95% Pricing
AP10184m-PEG4 NHS Ester333.33≥95% Pricing
AP10985m-PEG5-NHS ester377.39≥95% Pricing
AP11332m-PEG6-NHS ester421.44≥95% Pricing
AP11333m-PEG7-NHS ester465.5≥95% Pricing
AP10993m-PEG8-NHS ester509.55≥95% Pricing
AP11334m-PEG9-NHS ester553.6≥95% Pricing
AP11343m-PEG9 NHS succinate581.61≥95% Pricing
AP11335m-PEG10-NHS ester597.66≥95% Pricing
AP11336m-PEG11-NHS ester641.71≥95% Pricing
AP10185m-PEG12 NHS Ester685.76≥95% Pricing
AP11337m-PEG13-NHS ester729.81≥95% Pricing
AP11338m-PEG16-NHS ester861.97≥95% Pricing
AP11339m-PEG17-NHS ester906.03≥95% Pricing
AP11340m-PEG24-NHS ester1214.4≥95% Pricing
AP11341m-PEG25-NHS ester1258.45≥95% Pricing
AP11342m-PEG37-NHS ester1787.09≥95% Pricing
M-PEG-succinimidyl carbonate
AP10092m-PEG4-NHS carbonate305.28≥95% Pricing
AP10093m-PEG5-NHS carbonate349.33≥95% Pricing
AP11828m-PEG5-succinimidyl carbonate393.39≥95% Pricing
AP11829m-PEG8-succinimidyl carbonate525.55≥95% Pricing
Mal-Alkyl-NHS ester
AP10146Mal NHS ester266.21≥95% Pricing
AP10549Mal-C6-NHS ester308.29≥95% Pricing
AP10550Mal-C11-NHS ester378.42≥95% Pricing
Mal-amido-PEG-NHS ester
AP10938Mal-amido-PEG1 NHS ester381.34≥95% Pricing
AP11480Mal-amido-PEG2 NHS ester425.39≥95% Pricing
AP10939Mal-amido-PEG3 NHS ester469.45≥95% Pricing
AP10227Mal-amido-PEG4 NHS ester513.50≥95% Pricing
AP10940Mal-amido-PEG5 NHS ester557.55≥95% Pricing
AP11481Mal-amido-PEG6 NHS ester601.61≥95% Pricing
AP10941Mal-amido-PEG7 NHS ester645.66≥95% Pricing
AP10978Mal-amido-PEG8 NHS ester689.71≥95% Pricing
AP10942Mal-amido-PEG12 NHS ester865.92≥95% Pricing
AP10943Mal-amido-PEG24 NHS ester1394.56≥95% Pricing
Mal-PEG-NHS ester
AP11448Mal-PEG1-NHS ester310.26≥95% Pricing
AP11449Mal-PEG2-NHS ester354.32≥95% Pricing
AP10054Mal-PEG3-CH2 NHS ester384.34≥95% Pricing
AP11450Mal-PEG3-NHS ester398.37≥95% Pricing
AP10698Mal-PEG4-NHS ester442.42≥95% Pricing
AP11451Mal-PEG5-NHS ester486.47≥95% Pricing
AP11452Mal-PEG6-NHS ester530.53≥95% Pricing
AP11453Mal-PEG8-NHS ester618.63≥95% Pricing
AP11454Mal-PEG12-NHS ester794.85≥95% Pricing
other-PEG-NHS ester
AP13836Acridinium NHS ester632.6≥98% Pricing
Propargyl-PEG-CH2CO2-NHS
AP12280Propargyl-PEG4-CH2CO2-NHS343.33≥95% Pricing
AP12281Propargyl-PEG5-CH2CO2-NHS387.39≥95% Pricing
Propargyl-PEG-NHS ester
AP13740Alkyne NHS ester (hexynoic acid NHS ester)209.20≥95% Pricing
AP13852Propargyl-NHS Ester225.20≥95% Pricing
AP11026Propargyl-PEG1 NHS ester225.2≥95% Pricing
AP10918Propargyl-PEG2-NHS ester269.25≥95% Pricing
AP12275Propargyl-PEG3-NHS ester313.31≥95% Pricing
AP12276Propargyl-PEG4-NHS ester357.36≥95% Pricing
AP12277Propargyl-PEG5-NHS ester401.41≥95% Pricing
AP10998Propargyl-PEG6-NHS ester445.47≥95% Pricing
AP12278Propargyl-PEG7-NHS ester489.52≥95% Pricing
AP12279Propargyl-PEG8-NHS ester533.57≥95% Pricing
SPDP-PEG-NHS-ester
AP10042SPDP acid NHS ester312.37≥98% Pricing
AP11950SPDP-C6-NHS ester425.52≥95% Pricing
AP11951SPDP-C6-Sulfo-NHS ester527.56≥95% Pricing
AP11433SPDP-PEG4-NHS ester559.65≥95% Pricing
AP11832SPDP-C6-Gly-Leu-NHS ester595.73≥95% Pricing
AP11434SPDP-PEG6-NHS ester647.76≥95% Pricing
AP11435SPDP-PEG8-NHS ester735.86≥95% Pricing
AP11436SPDP-PEG12-NHS ester912.07≥95% Pricing
AP13379SPDP-PEG-24-NHS ester1439.7≥95% Pricing
AP13380SPDP-PEG36-NHS ester1968.4≥92% Pricing
t-Boc-aliphatic-NHS ester
AP143146-(tert-Butoxy)-6-oxohexanoic NHS ester299.30≥95% Pricing
AP1431510-(tert-Butoxy)-10-oxodecanoic NHS ester355.40≥95% Pricing
AP11963t-butyl-octadecanedioate-NHS ester467.65≥95% Pricing
t-Boc-Aminooxy-PEG-NHS ester
AP12063t-Boc-Aminooxy-PEG4-NHS ester478.5≥95% Pricing
AP12064t-Boc-Aminooxy-PEG12-NHS ester830.92≥95% Pricing
t-Boc-N-Amido-PEG-CH2CO2-NHS ester
AP10906t-Boc-N-Amido-PEG1-CH2CO2-NHS ester316.31≥95% Pricing
AP10907t-Boc-N-Amido-PEG2-CH2CO2-NHS ester360.36≥95% Pricing
AP10908t-Boc-N-Amido-PEG3-CH2CO2-NHS ester404.41≥95% Pricing
AP10909t-Boc-N-Amido-PEG4-CH2CO2-NHS ester448.47≥95% Pricing
AP10910t-Boc-N-Amido-PEG5-CH2CO2-NHS ester492.52≥95% Pricing
AP10911t-Boc-N-Amido-PEG6-CH2CO2-NHS ester536.58≥95% Pricing
AP10912t-Boc-N-Amido-PEG7-CH2CO2-NHS ester580.63≥95% Pricing
t-Boc-N-amido-PEG-NHS ester
AP11614t-Boc-N-amido-PEG1-NHS ester330.34≥95% Pricing
AP10712T-Boc-N-amido-PEG2-NHS ester374.39≥95% Pricing
AP11615t-Boc-N-amido-PEG3-NHS ester418.44≥95% Pricing
AP10902t-Boc-N-Amido-PEG4-NHS ester462.49≥95% Pricing
AP11616t-Boc-N-amido-PEG5-NHS ester506.55≥95% Pricing
AP10903t-Boc-N-Amido-PEG6-NHS ester550.60≥95% Pricing
AP10904t-Boc-N-Amido-PEG7-NHS ester594.66≥95% Pricing
AP10905t-Boc-N-Amido-PEG8-NHS ester638.70≥95% Pricing
AP11617t-Boc-N-amido-PEG10-NHS ester726.81≥95% Pricing
AP14097t-Boc-N-amido-PEG12-NHS ester814.90≥95% Pricing
AP14099t-Boc-N-amido-PEG16-NHS ester991.10≥95% Pricing
t-Butoxycarbonyl-PEG-NHS ester
AP11830t-Butoxycarbonyl-PEG1-NHS ester315.32≥95% Pricing
AP13412t-Butoxycarbonyl-PEG2-NHS ester359.4≥95% Pricing
AP13383t-Butoxycarbonyl-PEG3-NHS ester403.4≥98% Pricing
AP11831t-Butoxycarbonyl-PEG4-NHS ester447.48≥95% Pricing
TCO-PEG-NHS ester
AP13857TCO-NHS Ester (equatorial)267.28≥95% Pricing
AP12681TCO-NHS Ester (axial)267.28≥95% Pricing
AP10003TCO-NHS ester267.30≥95% Pricing
AP13056TCO-benzoyl-NHS ester357.4≥95% Pricing
AP10815TCO-PEG1-NHS ester382.41≥95% Pricing
AP10816TCO-PEG2-NHS ester426.46≥95% Pricing
AP10817TCO-PEG3-NHS ester470.52≥95% Pricing
AP10101TCO-PEG4-CH2 NHS ester500.54≥95% Pricing
AP10818TCO-PEG4-NHS ester514.57≥95% Pricing
AP13228TCO-PEG2-Sulfo-NHS ester528.5≥95% Pricing
AP10099TCO-PEG5 NHS ester558.62≥95% Pricing
AP10820TCO-PEG6-NHS ester602.67≥95% Pricing
AP10821TCO-PEG7-NHS ester646.73≥95% Pricing
AP11858TCO-PEG8-NHS ester690.78≥95% Pricing
AP11859TCO-PEG12-NHS ester867≥95% Pricing
AP11860TCO-PEG24-NHS ester1395.63≥95% Pricing
AP13221TCO-PEG36-NHS ester1924.3≥95% Pricing
Tetrazine-PEG-NHS ester
AP10691Tetrazine-NHS ester313.27≥95% Pricing
AP10692Methyltetrazine-NHS ester327.30≥95% Pricing
AP11842Methyltetrazine-Sulfo-NHS ester429.34≥95% Pricing
AP10720Methyltetrazine-PEG4-NHS ester533.53≥95% Pricing
AP11843Tetrazine-PEG5-NHS ester604.62≥95% Pricing
AP11844Methyltetrazine-PEG8-NHS ester709.75≥95% Pricing
AP11845Methyltetrazine-PEG12-NHS ester885.96≥95% Pricing
AP11846Methyltetrazine-PEG24-NHS ester1414.6≥95% Pricing
Thalidomide-O-PEG-NHS ester
AP13384Thalidomide-O-PEG2-NHS ester531.5≥98% Pricing
AP12126Thalidomide-O-PEG4-NHS ester619.58≥95% Pricing
AP13385Thalidomide-O-PEG6-NHS ester707.7≥98% Pricing

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