Lipid PEG Linkers(PEG Lipid), also known as PEGylated lipids, are a class of amphiphilic molecules that have gained significant attention in the field of drug delivery.
These molecules consist of a hydrophilic polyethylene glycol (PEG) moiety attached to a hydrophobic lipid tail, creating a unique structure that allows for both water and lipid solubility. This property makes it an attractive option for enhancing the stability, pharmacokinetics, and bioavailability of a wide range of therapeutics, including proteins, peptides, and small molecules.
Two key characteristics of lipid PEG that contribute to its potential as a drug delivery system are its biocompatibility and ability to self-assemble into stable structures such as micelles or liposomes.
Overall, It has emerged as a promising tool in the development of next-generation drug delivery systems, with the potential to improve the efficacy and safety of various therapeutic agents.