Carboxylic Acid PEG is a versatile tool in ADC. It has an acid group on one end of the peg chain and another functional group on the other end.
COOH Carboxylic acid PEG has excellent water solubility and can easily react with amine-containing bio-molecules under amide coupling conditions. It can also be converted to amine-reactive forms, such as N-hydroxysuccinimide ester (NHS ester), pentafluorophenol ester (PFP), tetrafluorophenol (TFP) ester, and acid chloride. They are all widely used in bioconjugation, drug delivery technologies, and drug property modifications.
AxisPharm offers 5000+ polyethylene glycol PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
Acid PEG
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