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Mal-Alkyl-t-Boc-amine is a chemical compound that belongs to the class of amine derivatives. This compound contains a tert-butyloxycarbonyl (Boc) group, an alkyl chain, and a maleimide functional group. The Boc group serves as a protective group for the amine, while the maleimide group is a highly reactive electrophile that can react with thiol-containing molecules through Michael addition.

Mal-Alkyl-t-Boc-amine has found extensive use in the field of pharmaceutical research and development, particularly in the development of novel bioconjugates. Its unique chemical properties allow for the selective modification of proteins, peptides, and other biomolecules with thiol-containing compounds, such as antibodies or enzymes, via a stable covalent bond. This process is commonly referred to as thiol-maleimide coupling, and it has become a critical tool for the preparation of various bioconjugates for biomedical applications.

In addition to its use in bioconjugation, Mal-Alkyl-t-Boc-amine has also been utilized in the development of drug delivery systems. Its maleimide functional group allows for site-specific conjugation of therapeutics to the surface of drug carriers, such as liposomes or nanoparticles, resulting in enhanced targeting and therapeutic efficacy.


Cat# Name Structure M.W. Purity Pricing
AP116306-Mal-C6-Boc-Amine296.37≥95% Pricing

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