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Folate (folic acid) PEG linkers are PEG reagents with a folic acid functional group. The folate receptor is a membrane-bound protein that has high affinity for folic acid. This receptor serves as a receptor-mediated transport system of folic acid into cancer cells and cells associated with inflammation (e.g., macrophages). As a basic component of cell metabolism in the synthesis of both DNA and proteins, folate is believed to be essential for maintaining an elevated metabolic process.
Unlike most normal cells in the body which have little to no affinity for folate, cancer cells have a high expression of folate receptor alpha. Because of these attributes, folate based drug delivery, imaging systems, and diagnostic systems are in various stages of development worldwide.
AxisPharm is the worldwide leading provider of folate related linkers for crosslinking technologies. We have the largest collection of in stock folate PEG linkers to facilitate folate receptor related research.

Cat# Name Structure M.W. Purity Pricing
AP13634DSPE-PEG- Folate, MW 1K1000≥95% Pricing
AP13664DSPE-PEG- Folate, MW 2K2000≥95% Pricing
AP13679DSPE-PEG- Folate, MW 3.4K3400≥95% Pricing
AP13689DSPE-PEG- Folate, MW 5K5000≥95% Pricing
AP11022Folate-amido-C2-amine-endo-BCN659.69≥95% Pricing
AP12981Folate-PEG1 DBCO amide814.86≥95% Pricing
AP15245Folate-PEG2 DBCO amide858.86≥95% Pricing
AP12975Folate-PEG1 acid556.54≥95% Pricing
AP12976Folate-PEG2 acid600.59≥95% Pricing
AP10010Folate-PEG3-Amine571.59≥95% Pricing
AP10012Folate-PEG2-Azide597.58≥95% Pricing
AP10561Folate-PEG3-Azide641.64≥95% Pricing
AP10559Folate-PEG4-Azide685.70≥95% Pricing
AP12977Folate-PEG1-hydrazide570.57≥95% Pricing
AP12978Folate-PEG2-hydrazide614.62≥95% Pricing
AP12982Folate-PEG1-Mal607.58≥95% Pricing
AP12983Folate-PEG2-Mal651.64≥95% Pricing
Folate-PEG-NHS ester
AP10011Folate PEG3 NHS ester741.71≥95% Pricing
AP12979Folate-PEG1-oxyamine543.54≥95% Pricing
AP12980Folate-PEG2-oxyamine587.59≥95% Pricing
AP10009Folate-PEG3-Propargyl610.62≥95% Pricing
AP15264Propargyl Folate478.469≥95% Pricing
AP15251Folate-PEG4-alkyne654.67≥95% Pricing

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