Folate-PEG2-Mal is a small molecule linker that contains several functional groups, including a folate group, a PEG (polyethylene glycol) chain, and a maleimide (Mal) group. The folate group can specifically bind to folate receptors that are overexpressed on the surface of certain cancer cells, while the PEG chain can improve the solubility and biocompatibility of the compound.
The maleimide group in Folate-PEG2-Mal is particularly useful, as it can react with sulfhydryl groups on other molecules, forming stable thioether linkages. This property makes Folate-PEG2-Mal a valuable tool for bioconjugation and drug delivery applications, as it can be used to attach drugs or other molecules to folate-targeted nanoparticles, thus improving their specificity and efficacy.
Folate-PEG2-Mal is a small molecule linker with a folate targeting group, a PEG chain, and a maleimide group, which can be used to selectively deliver drugs or other molecules to folate receptor-overexpressing cancer cells. The maleimide group allows for easy bioconjugation and modification of the linker, making it a valuable tool for drug delivery and other biomedical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
