Amine reactive linkers are a type of small molecule compound that is used in a variety of biological research applications, particularly in the field of drug development. These linkers are designed to react specifically with amine functional groups on target molecules, allowing them to be selectively conjugated with other compounds or biomolecules.
Amine reactive linkers can be classified into several categories based on their specific chemical properties and functional groups. For example, some amine reactive linkers contain maleimide groups, which are highly reactive with thiols and are commonly used for conjugation with antibodies and other proteins. Others contain N-hydroxysuccinimide (NHS) esters, which are highly reactive with primary amines and are commonly used for labeling peptides and small molecules.