tert-butyl 2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethylcarbamate contains a maleimide group and a Boc-protected amine group. The protected amine can be deprotected by acidic conditions. The maleimide group reacts specifically with a thiol group to form a covalent S-C bond at pH 6.5-7.5, enabling the conjugation of biomolecule with cysteine thiol residues.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.