Cleavable Linkers

Cleavable linkers play a crucial role in the success of antibody-drug conjugates. It determines the fate of the cytotoxic drug in the biological system. In order to make the ADC effective, it requires the linkers to be stable enough in the blood circulation for a substantial amount of time to avoid side toxicity and to allow ADC to reach the target. It also requires the linkers to be labile so that they efficiently release corresponding payload in the tumor environment.

Cleavable Linkers (in stock)

Peptide Linkers

β-Glucuronide Linkers

Ala-Ala-Asn-pab peptide Linkers

Val-ala linkers

Val-Cit-PAB Linkers

Catalog No. Name Structure M.W. Purity Pricing
AP10895 BCN-PEG1-Val-Cit-OH BCN-PEG1-Val-Cit-OH 565.67 95% Pricing

AP10895

BCN-PEG1-Val-Cit-OH
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
AP10896 BCN-PEG1-Val-Cit-PABC-OH BCN-PEG1-Val-Cit-PABC-OH 670.81 95% Pricing

AP10896

BCN-PEG1-Val-Cit-PABC-OH
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
AP10897 BCN-PEG1-Val-Cit-PABC-PNP BCN-PEG1-Val-Cit-PABC-PNP 835.91 95% Pricing

AP10897

BCN-PEG1-Val-Cit-PABC-PNP
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
Val-Cit-PAB Linkers
AP10899 DBCO-PEG1-Val-Cit-PABC-OH DBCO-PEG1-Val-Cit-PABC-OH 694.83 95% Pricing

AP10899

DBCO-PEG1-Val-Cit-PABC-OH
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
Val-ala linkers
AP10878 Alloc-Val-Ala-PAB Alloc-Val-Ala-PAB 377.44 95% Pricing

AP10878

Alloc-Val-Ala-PAB
Unit Price(USD) Quantity
500 mg $654.00
1000 mg $980.00
AP10891 Azido-PEG1-Val-Cit-PABC-PNP Azido-PEG1-Val-Cit-PABC-PNP 685.7 95% Pricing

AP10891

Azido-PEG1-Val-Cit-PABC-PNP
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
AP10892 TCO-PEG1-Val-Cit-OH TCO-PEG1-Val-Cit-OH 541.65 95% Pricing

AP10892

TCO-PEG1-Val-Cit-OH
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
AP10873 Boc-Val-Ala-PAB Boc-Val-Ala-PAB 393.48 95% Pricing

AP10873

Boc-Val-Ala-PAB
Unit Price(USD) Quantity
250 mg $400.00
500 mg $600.00
1000 mg $980.00
AP10877 Mc-Val-Ala-PAB-PNP Mc-Val-Ala-PAB-PNP 651.67 95% Pricing

AP10877

Mc-Val-Ala-PAB-PNP
Unit Price(USD) Quantity
100 mg $374.00
250 mg $747.00
500 mg $1,120.00
1000 mg $1,680.00
AP10894 TCO-PEG1-Val-Cit-PABC-PNP TCO-PEG1-Val-Cit-PABC-PNP 811.89 95% Pricing

AP10894

TCO-PEG1-Val-Cit-PABC-PNP
Unit Price(USD) Quantity
100 mg $425.00
250 mg $850.00
500 mg $1,275.00
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