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Cleavable linkers are an important class of molecules that are widely used in various fields such as drug discovery, chemical biology, and materials science. These linkers serve as a connecting bridge between two or more molecular entities, and can be selectively cleaved under specific conditions, resulting in the release of the attached molecules. This property makes them an attractive tool for targeted drug delivery, imaging, and controlled release of biologically active compounds.

One of the key features of cleavable linkers is their ability to respond to specific stimuli such as enzymes, pH, light, or heat, which allows for precise control over the timing and location of the molecule release. The choice of the appropriate cleavable linker depends on the nature of the attached molecules, the desired rate of release, and the intended application.

PEG Applications

pegylation
ADC-Conjugation
Click-Chemistry
Dye-Labeling
Drug-Delivery

Top 10 selling High purity Cleavable Linkers

Cat# Name Structure M.W. Purity Pricing
AP10507Biotin-amine286.40≥95% Pricing
AP10153(2S,3S,4S,5R,6S)-methyl-6-(2-(3-((Fmoc-amino)propanamido)-4-PNP-3,4,5-triacetoxy-tetrahydro-2H-pyran-2-carboxylate913.83≥95% Pricing
AP10231Thiol-PEG3-Azide235.31≥95% Pricing
AP10352Fmoc-NH-PEG28-acid1544.81≥95% Pricing
AP10020Fmoc-Ala-Ala-Asn(Trt)-OH738.83≥95% Pricing
AP10102TCO-triethoxysilane373.56≥95% Pricing
AP10229Thiol-PEG4-alcohol210.29≥95% Pricing
AP10737endo-BCN-PEG4-t-butyl ester497.62≥95% Pricing
AP10548endo-BCN-NHS carbonate291.30≥95% Pricing
AP10903t-Boc-N-Amido-PEG6-NHS ester550.60≥95% Pricing

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