SPDP PEG linker is a PEG reagent(crosslinker) , which have a reducible (cleavable) disulfide bond. Pyridyldithiol group enables disulfide linkage with reduced cysteines and other sulfhydryl groups, providing a stable but cleavable bond.
The containing polyethylene glycol (PEG) spacer arms offer greater solubility to the crosslinker and the linked proteins compared to crosslinkers having only hydrocarbon spacers. SPDP reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT).
AxisPharm offers a range of high purity SPDP PEG reagents with different linker lengths.Different kinds of PEG Reagents may be available by custom synthesis. Fast delivery – Overnight shipping．