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SPDP PEG linker is a PEG reagent(crosslinker) , which have a reducible (cleavable) disulfide bond. Pyridyldithiol group enables disulfide linkage with reduced cysteines and other sulfhydryl groups, providing a stable but cleavable bond.
The containing polyethylene glycol (PEG) spacer arms offer greater solubility to the crosslinker and the linked proteins compared to crosslinkers having only hydrocarbon spacers. SPDP reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT).
AxisPharm offers a range of high purity SPDP PEG reagents with different linker lengths.Different kinds of PEG Reagents may be available by custom synthesis. Fast delivery – Overnight shipping．

SPDP PEG
  • SPDP-PEG-NHS-ester
  • SPDP-PEG-TCO
  • SPDP-PEG-acid
  • SPDP-PEG-t-Butyl ester
Cat# Name Structure M.W. Purity Pricing
SPDP-PEG-acid
AP10041SPDP acid
Quick viewSPDP acid
215.30≥98% Pricing
AP108614-methyl-4-(pyridin-2-yldisulfaneyl)pentanoic acid
Quick view4-methyl-4-(pyridin-2-yldisulfaneyl)pentanoic acid
257.37≥95% Pricing
AP10427SPDP-PEG4-acid
Quick viewSPDP-PEG4-acid
462.58≥95% Pricing
AP10428SPDP-PEG5-acid
Quick viewSPDP-PEG5-acid
506.63≥95% Pricing
AP10429SPDP-PEG7-acid
Quick viewSPDP-PEG7-acid
594.74≥95% Pricing
AP10038SPDP-PEG8-acid
Quick viewSPDP-PEG8-acid
638.79≥98% Pricing
AP10430SPDP-PEG9-acid
Quick viewSPDP-PEG9-acid
682.84≥95% Pricing
AP11430SPDP-PEG12-acid
Quick viewSPDP-PEG12-acid
815≥95% Pricing
AP11431SPDP-PEG24-acid
Quick viewSPDP-PEG24-acid
1343.64≥95% Pricing
AP11432SPDP-PEG36-acid
Quick viewSPDP-PEG36-acid
1872.27≥95% Pricing
SPDP-PEG-NHS-ester
AP10042SPDP acid NHS ester
Quick viewSPDP acid NHS ester
312.37≥98% Pricing
AP108672,5-dioxopyrrolidin-1-yl 4-methyl-4-(pyridin-2-yldisulfaneyl)pentanoate
Quick view2,5-dioxopyrrolidin-1-yl 4-methyl-4-(pyridin-2-yldisulfaneyl)pentanoate
354.45≥95% Pricing
AP11950SPDP-C6-NHS ester
Quick viewSPDP-C6-NHS ester
425.52≥95% Pricing
AP11951SPDP-C6-Sulfo-NHS ester
Quick viewSPDP-C6-Sulfo-NHS ester
527.56≥95% Pricing
AP11433SPDP-PEG4-NHS ester
Quick viewSPDP-PEG4-NHS ester
559.65≥95% Pricing
AP11434SPDP-PEG6-NHS ester
Quick viewSPDP-PEG6-NHS ester
647.76≥95% Pricing
AP11435SPDP-PEG8-NHS ester
Quick viewSPDP-PEG8-NHS ester
735.86≥95% Pricing
AP11436SPDP-PEG12-NHS ester
Quick viewSPDP-PEG12-NHS ester
912.07≥95% Pricing
SPDP-PEG-t-Butyl ester
AP10037SPDP-PEG8-tBu ester
Quick viewSPDP-PEG8-tBu ester
694.90≥98% Pricing
SPDP-PEG-TCO
AP10144SPDP-NH-PEG2-TCO
Quick viewSPDP-NH-PEG2-TCO
497.67≥95% Pricing

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