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Peptide PEG linkers are protease-sensitivity linkers (also called enzymatically cleavable linkers). They comprise of either a di-, tri- or tetra-peptide that is recognized and cleaved by lysosomal enzymes to ensure the intracellular drug release once the ADC is internalized to the lysosome. The PEG moiety improves the aqueous solubility of the resulting bioconjugate and helps avoid protein aggregation.

AxisPharm has a large collection of PEGylated peptide reagents in stock. Custom syntheses of peptide PEG are available upon request.

Peptide Linkers
  • Ala-Ala-Asn-pab Linkers
  • Lipid-PEG-peptide
  • Pomalidomide-PEG-CH2COOH
  • TCO-PEG-peptide
  • Tetrazine-PEG-peptide
  • Val-Cit PEG
  • Val-Gly
  • Val-ala linkers
Cat# Name Structure M.W. Purity Pricing
Ala-Ala-Asn-pab Linkers
AP10004MC-Ala-Ala-Asn(Trt)-OH709.79≥98% Pricing
AP10020Fmoc-Ala-Ala-Asn(Trt)-OH738.83≥95% Pricing
AP10016Fmoc-Ala-Ala-Asn-PAB-PNP766.75≥95% Pricing
AP10013Fmoc-Ala-Ala-Asn(Trt)-PAB843.97≥95% Pricing
AP10014Fmoc-Ala-Ala-Asn(Trt)-PAB-PNP1009.07≥95% Pricing
Lipid-PEG-peptide
AP10812N’-Boc-N-(Gly-Oleoyl)-Lys567.80≥95% Pricing
AP10314Oleoyl-Gly-Lys-(m-PEG11)-amine965.32≥95% Pricing
Pomalidomide-PEG-CH2COOH
AP12999Pomalidomide-PEG2-CH2COOH419.39≥95% Pricing
AP12996Pomalidomide-PEG3-CH2COOH463.44≥95% Pricing
AP12998Pomalidomide-PEG4-CH2COOH507.5≥95% Pricing
TCO-PEG-peptide
AP11871Gly-Gly-Gly-PEG3-TCO515.61≥95% Pricing
AP13232TCO-PEG4-Fmoc-Gly-Gly-Gly781.9≥95% Pricing
Tetrazine-PEG-peptide
AP11854Gly-Gly-Gly-PEG4-methyltetrazine534.57≥95% Pricing
Val-ala linkers
AP13070Boc-Val-Ala-OH288.34≥95% Pricing
AP10874Val-Ala-PAB-OH293.36≥95% Pricing
AP131284-Pentynoyl-Val-Ala-PAB-OH373.45≥95% Pricing
AP10878Alloc-Val-Ala-PAB-OH377.44≥95% Pricing
AP10873Boc-Val-Ala-PAB-OH393.48≥95% Pricing
AP131296-Azidohexanoyl-Val-Ala-PAB-OH432.52≥95% Pricing
AP12527Mal-Val-Ala-PAB444.48≥95% Pricing
AP10876MC-Val-Ala-PAB-OH486.57≥95% Pricing
AP12525Acid but-2-enecarbonyl-Val-Ala-PAB504.58≥95% Pricing
AP10875Fmoc-Val-Ala-PAB-OH515.60≥95% Pricing
AP125242-bromoacrylic-NH-hexyl-Val-Ala-PAB539.46≥95% Pricing
AP10879Alloc-Val-Ala-PAB-PNP542.54≥95% Pricing

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