Folate PEG Linkers combine folic acid and PEG to target folate receptors on cancer and inflammatory cells. They enable precise drug delivery, advanced imaging, receptor quantification, and selective cell degradation, enhancing treatment and diagnostics.
Folate PEG
Folate PEG Linkers: Transforming Drug Delivery, Diagnostics, and Selective Degradation
What Are Folate PEG Linkers?
Folate PEG linkers combine polyethylene glycol (PEG) with folic acid to target folate receptors commonly found on cancer and inflammation-related cells.How Do They Work?
Folate receptors naturally bind folic acid, helping transport it into cells. By linking folic acid with PEG, these linkers precisely target these receptors for drug delivery, advanced diagnostics, and selective degradation of harmful cells.Key Applications:
- Targeted Drug Delivery: Direct therapeutic agents to cancerous and inflammatory cells, improving treatment while minimizing harm to healthy cells.
- Advanced Imaging: Enhance disease tracking and diagnostics, offering critical insights.
- Receptor Quantification: Use folate PEG probes to measure folate receptor density, providing data on cell behavior.
- Selective Degradation: Apply folate receptor chimeras for the targeted degradation of specific cells, improving therapeutic outcomes.
- Enhanced Research: Study cell metabolism, DNA synthesis, and protein production by targeting folate receptors.