The maleimide group reacts specifically with a thiol group to form a covalent C-S bond, enabling the bioconjugation with a thiol bearing molecules. The endo-BCN reacts with azide-bearing compounds or biomolecules via copper free Click Chemistry to yield a stable triazole linkage. The PEG spacer increase the solubility of the resulting complex in aqueous media.
AxisPharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.