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Mal-amido-PEG-acetic acid has been extensively utilized in the development of novel drug delivery systems, such as antibody-drug conjugates (ADCs) and protein-polymer conjugates. Its maleimide group allows for the selective conjugation of thiol-containing biomolecules, such as cysteine residues in proteins, through a thiol-maleimide reaction. This covalent attachment of therapeutic agents to PEG chains via Mal-amido-PEG-acetic acid can improve stability, solubility, and bioavailability, leading to enhanced therapeutic efficacy and reduced side effects.

Moreover, Mal-amido-PEG-acetic acid can be used in the synthesis of multifunctional bioconjugates for targeted drug delivery. By coupling targeting moieties such as antibodies or peptides to it, and then subsequently to a therapeutic agent, a conjugate can be designed to selectively target a particular cell type or tissue, leading to improved drug delivery and reduced toxicity.

Mal-amido-PEG-acetic acid

Cat# Name Structure M.W. Purity Pricing
AP10923Mal-propionylamido-PEG1-acetic acid270.24≥95% Pricing
AP10924Mal-propionylamido-PEG2-acetic acid314.29≥95% Pricing
AP10925Mal-propionylamido-PEG3-acetic acid358.35≥95% Pricing
AP10926Mal-propionylamido-PEG4-acetic acid402.4≥95% Pricing
AP10927Mal-propionylamido-PEG5-acetic acid446.45≥95% Pricing
AP10928Mal-propionylamido-PEG6-acetic acid490.51≥95% Pricing
AP10929Mal-propionylamido-PEG7-acetic acid534.56≥95% Pricing
AP10930Mal-propionylamido-PEG8-acetic acid578.61≥95% Pricing

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