Silane PEG linkers are chemical compounds that belong to the class of polyethylene glycol (PEG) derivatives. These compounds consist of a PEG chain attached to a silane functional group (-SiX3) that can be used to covalently bind to various surfaces.
They have gained popularity in the field of pharmaceutical research and development due to their ability to modify the surface properties of nanoparticles, liposomes, and other drug delivery systems. By attaching PEG chains to the surface of these particles through them, researchers can improve their stability, biocompatibility, and circulation time in the bloodstream.
Silane Reagents have been utilized in the development of biosensors and diagnostic assays. By immobilizing biomolecules onto the surface of a sensor or assay platform via silane PEG linkers, researchers can enhance sensitivity, selectivity, and stability of the assay.