Small Molecule Analysis: Expert Mass Spectrometry & Chromatography

Welcome to AxisPharm, your premier partner for precise small molecule analysis. We specialize in advanced mass spectrometry and chromatography techniques, including GC-MS, LC-MS/MS quantification, and NIST GC-MS data analysis, to deliver accurate and reliable results for pharmaceutical development and research.

Our Services

1. Mass Spectrometry (MS)

Mass spectrometry is essential for detailed small molecule analysis:

  • High-Resolution MS: Provides precise molecular weight and structural information for accurate identification.
  • Quantitative Analysis: Measures small molecule concentrations with high sensitivity and accuracy.
  • Impurity Profiling: Identifies and characterizes impurities to ensure product purity and compliance.
  • MS/MS (Tandem Mass Spectrometry): Offers in-depth analysis of complex mixtures with enhanced molecular insights.

2. Chromatography

Our chromatography services are key to separating and analyzing small molecules:

  • High-Performance Liquid Chromatography (HPLC): Delivers high-resolution separation and quantification of small molecules.
  • Gas Chromatography (GC): Ideal for analyzing volatile and semi-volatile compounds, providing precise separation and comprehensive analysis.
  • GC-MS Integration: Combines gas chromatography with mass spectrometry for detailed analysis of complex mixtures, including environmental and synthetic compounds.
  • LC-MS Integration: Combines liquid chromatography with mass spectrometry for comprehensive analysis and detailed molecular identification.

3. LC-MS/MS Quantification

LC-MS/MS (Liquid Chromatography-Mass Spectrometry/Mass Spectrometry) is a powerful tool for accurate quantification:

  • Quantitative Analysis: Provides highly accurate measurements of small molecule concentrations, essential for pharmacokinetics and bioanalysis.
  • Sensitivity and Specificity: Ensures precise detection and quantification even at low concentrations.
  • Complex Sample Analysis: Handles complex samples with multiple components, delivering reliable and reproducible results.

4. GC-MS Analysis

Gas Chromatography-Mass Spectrometry (GC-MS) is key for analyzing volatile and semi-volatile compounds:

  • Volatile Compound Analysis: Efficiently separates and identifies volatile compounds, ideal for environmental, forensic, and food analysis.
  • Complex Mixture Analysis: Provides detailed molecular insights into complex mixtures, including synthetic and natural products.
  • Environmental and Industrial Applications: Analyzes pollutants, pesticides, and other environmental contaminants.

5. NIST GC-MS Data Analysis

We offer comprehensive NIST GC-MS data analysis services:

  • NIST Library Matching: Utilizes the NIST Mass Spectral Library to accurately identify compounds based on their mass spectra.
  • Enhanced Compound Identification: Provides detailed analysis and matching against a comprehensive database of known spectra.
  • High-Resolution Data Analysis: Ensures accurate interpretation of complex GC-MS data for precise compound identification.

Categories of Small Molecules We Analyze

  • Pharmaceuticals: Drugs, medications, and biologics.
  • Metabolites: Primary and secondary metabolites.
  • Natural Products: Plant and marine-derived compounds.
  • Synthetic Chemicals: Organic and inorganic chemicals.
  • Environmental Contaminants: Pesticides and pollutants.
  • Food Additives: Flavorings and preservatives.
  • Cosmetic Ingredients: Active ingredients and functional additives.
  • Chemical Probes: Reagents and labeling agents.
  • Drug Metabolites: Phase I and Phase II metabolites.
  • Therapeutic Agents: Chemotherapy agents and hormones.

For a detailed list of small molecules covered by Axis Pharm, please click here.

Why Choose Axis Pharm?

  • Precision and Accuracy: Our advanced technology ensures reliable molecular identification and quantification.
  • Experienced Team: Benefit from our expert scientists’ extensive knowledge and skills.
  • State-of-the-Art Equipment: We use the latest mass spectrometry and chromatography tools for optimal performance.
  • Customized Solutions: Tailored analysis services to meet your specific requirements.
  • Regulatory Compliance: We help ensure your products meet international standards with our comprehensive compliance services.

Contact Us

Ready to enhance your small molecule analysis? Contact Axis Pharm today to learn more about our mass spectrometry, chromatography, and LC-MS/MS quantification services.

Axis Pharm—Your Expert in Small Molecule Analysis with Advanced Mass Spectrometry and Chromatography.