Dde Cleavable Linkers are a type of chemical linker that are widely used in bioconjugation applications to attach molecules to a target protein or peptide. These linkers are highly versatile and can be easily incorporated into a wide range of molecules. The Dde group is specifically used as a protecting group in organic chemistry, allowing for selective deprotection using hydrazine or hydroxylamine. This property makes Dde Cleavable Linkers an attractive option for targeted drug delivery and imaging applications, where precision and specificity are crucial. Key advantages of Dde Cleavable Linkers include their stability in physiological conditions, high yield of cleavage, and low toxicity. The use of these linkers has been expanding in recent years, with promising results in various fields such as cancer therapy, drug discovery, and molecular imaging.