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Mal-PEG-PFP ester is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains two functional groups, namely, maleimide and pentafluorophenyl (PFP) ester. The maleimide group is known for its ability to react with thiol-containing molecules, while the PFP ester group is known for its ability to react with amine-containing molecules, making Mal-PEG-PFP ester a versatile tool in the field of pharmaceutical research and development.

Mal-PEG-PFP ester has been extensively utilized in the development of novel drug conjugates and bioconjugation strategies. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as proteins and peptides, to PEG chains via maleimide-thiol or PFP-amine chemistry. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced side effects.

Mal-PEG-PFP ester

Cat# Name Structure M.W. Purity Pricing
AP114916-Maleimidocaproic acid PFP ester377.27≥95% Pricing
AP11455Mal-PEG1-PFP379.24≥95% Pricing
AP11456Mal-PEG2-PFP423.29≥95% Pricing
AP11457Mal-PEG3-PFP467.35≥95% Pricing
AP11458Mal-PEG4-PFP511.4≥95% Pricing
AP11459Mal-PEG5-PFP555.45≥95% Pricing
AP11460Mal-PEG6-PFP599.5≥95% Pricing

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