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Bis-Mal-Lysine-PEG (BML-PEG) is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains two lysine amino acids linked to a PEG chain through maleimide functional groups. The maleimide group is known for its ability to react specifically with thiol groups (-SH) on biomolecules, making BML-PEG a useful tool in the field of pharmaceutical research and development.

BML-PEG has been extensively utilized in the development of targeted drug delivery systems, such as antibody-drug conjugates (ADCs). ADCs are designed to selectively deliver cytotoxic drugs to cancer cells, while sparing healthy tissues. BML-PEG plays a critical role in the design of ADCs by providing a platform for the site-specific conjugation of the drug to the antibody.

The lysine amino acids in BML-PEG play a key role in the stability of the conjugate, as they can form stable amide bonds with the antibody. This results in a stable and homogeneous ADC product that exhibits improved pharmacokinetic properties and therapeutic efficacy.


Cat# Name Structure M.W. Purity Pricing
AP11496Bis-Mal-Lysine-PEG4-acid695.72≥95% Pricing
AP11497Bis-Mal-Lysine-PEG4-TFP ester843.78≥95% Pricing

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