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Folate (Folic Acid) PEG Linkers are PEG reagents with folic acid functionality. The folate receptor is a membrane-bound protein with high affinity for folate. This receptor acts as a receptor-mediated folate transport system into cancer cells and cells associated with inflammation (eg, macrophages). As an essential component of cellular metabolism in DNA and protein synthesis, folic acid is considered necessary to maintain elevated metabolic processes. Unlike most normal cells in the body that have little affinity for folate, cancer cells have highly expressed folate receptor alpha. Because of these properties, folic acid (folate) can selectively bind to folate receptors in a wide range of cancer tissues, such as ovarian cancer, lung cancer, and more. Folic acid-polyPEG can be used to design nanoparticle-based targeted cancer therapy via the folate receptor, thereby minimizing nonspecific uptake in normal cells.

AxisPharm is the world’s leading supplier of folate-related linkers for cross-linking technology. We have the largest collection of stocked folate PEG linkers to facilitate folate receptor related research.

Cat# Name Structure M.W. Purity Pricing
Cholesterol-PEG-Folate
AP15013Cholesterol-PEG-Folate, MW 1K1000≥95% Pricing
AP15014Cholesterol-PEG-Folate, MW 2K2000≥95% Pricing
AP15015Cholesterol-PEG-Folate, MW 3.4K3400≥95% Pricing
AP15016Cholesterol-PEG-Folate, MW 5K5000≥95% Pricing
Folate-PEG-amine
AP14486Folate-PEG-amine, MW 1K1000≥95% Pricing
AP14487Folate-PEG-amine, MW 2K2000≥95% Pricing
AP14488Folate-PEG-amine, MW 3.5K3500≥95% Pricing
AP14489Folate-PEG-amine, MW 5K5000≥95% Pricing
AP14490Folate-PEG-amine, MW 10K10000≥95% Pricing
Folate-PEG-Mal
AP13344Folate-PEG-Mal, MW 1K1000≥95% Pricing
AP13350Folate-PEG-Mal, MW 2K2000≥95% Pricing
AP13359Folate-PEG-Mal, MW 3.5K3500≥95% Pricing
AP13364Folate-PEG-Mal, MW 5K5000≥95% Pricing
AP13369Folate-PEG-Mal, MW 10K10000≥95% Pricing
Folate-PEG-OH
AP14909Folate-PEG-OH, MW 1K1000≥95% Pricing
AP14910Folate-PEG-OH, MW 2K2000≥95% Pricing
AP14911Folate-PEG-OH, MW 3.5K3500≥95% Pricing
AP14912Folate-PEG-OH, MW 5K5000≥95% Pricing
AP14913Folate-PEG-OH, MW 10K10000≥95% Pricing
Folate-PEG-Thiol
AP14914Folate-PEG-Thiol, MW 1K1000≥95% Pricing
AP14915Folate-PEG-Thiol, MW 2K2000≥95% Pricing
AP14916Folate-PEG-Thiol, MW 3.5K3500≥95% Pricing
AP14917Folate-PEG-Thiol, MW 5K5000≥95% Pricing
AP14918Folate-PEG-Thiol, MW 10K10000≥95% Pricing

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