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Mal-PEG-acid contains a carboxylic acid functional group (-COOH) attached to the end of a PEG chain, with a maleimide group (-NHCOCH=CH2) located at the other end of the chain.

The carboxylic acid group allows for the conjugation of Mal-PEG-acid to other molecules via peptide bond formation. The maleimide group, on the other hand, enables the conjugation of Mal-PEG-acid to thiol-containing molecules, such as cysteine residues in proteins and peptides. This unique combination of functional groups offers a wide range of possibilities for the development of novel drug delivery systems.

Mal-PEG-acid has been widely used in the pharmaceutical industry for the synthesis of antibody-drug conjugates (ADCs). ADCs are a promising class of targeted therapeutics that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs. Mal-PEG-acid is used to link the antibody to the drug molecule, creating a stable and selective conjugate that can specifically target cancer cells while sparing healthy cells.


Cat# Name Structure M.W. Purity Pricing
AP11444Mal-PEG1-acid213.19≥95% Pricing
AP10164Mal-PEG2-acid257.24≥95% Pricing
AP11445Mal-PEG3-acid301.3≥95% Pricing
AP10224Mal-PEG4-acid345.35≥95% Pricing
AP11446Mal-PEG5-acid389.4≥95% Pricing
AP10225Mal-PEG6-acid433.45≥95% Pricing
AP10226Mal-PEG8-acid521.56≥95% Pricing
AP11447Mal-PEG12-acid697.77≥95% Pricing

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