Cleavable linkers are an important class of molecules that are widely used in various fields such as drug discovery, chemical biology, and materials science. These linkers serve as a connecting bridge between two or more molecular entities, and can be selectively cleaved under specific conditions, resulting in the release of the attached molecules. This property makes them an attractive tool for targeted drug delivery, imaging, and controlled release of biologically active compounds.
One of the key features of cleavable linkers is their ability to respond to specific stimuli such as enzymes, pH, light, or heat, which allows for precise control over the timing and location of the molecule release. The choice of the appropriate cleavable linker depends on the nature of the attached molecules, the desired rate of release, and the intended application.