3,4-Dibromo-Mal-PEG8-t-butyl ester is a hydrophilic PEG species containing a dibromomaleimide group and a Boc-protected amine group. dibromomaleimide (DBM) allows for two points of attachment since each bromine can be substituted with a thiol to form two thioether bonds. The mild nature and selectivity of the DBM reaction allows for the use of sensitive biomolecular reagents in high efficiency. The Boc protecting group can be removed under acidic conditions and allows for the amine to further react with other species. The hydrophilic PEG linker can increase the compound’s water solubility properties in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.