Mal-(CH2)10-COOH CAS:57079-01-3, also known as Mal-dPEG11-acid, is a bifunctional linker molecule used in bioconjugation and protein modification applications. The reagent consists of a maleimide group, a 10-unit ethylene glycol (EG) chain, and a carboxylic acid group at the end of the linker.
The maleimide group is a highly reactive group that selectively reacts with sulfhydryl groups on biomolecules such as cysteine residues. The EG chain acts as a hydrophilic spacer, improving the solubility and accessibility of the target molecule. The carboxylic acid group provides an anchoring point for attachment to surfaces or other molecules.
Mal-(CH2)10-COOH is commonly used to attach biomolecules such as proteins or peptides to surfaces, for example, in the production of biosensors or immobilization of enzymes. It can also be used to introduce a spacer between two biomolecules, improving their interactions or accessibility.
Mal-(CH2)10-COOH is a white to off-white powder that is soluble in a range of polar solvents, such as DMSO, DMF, or ethanol. It should be stored at -20°C in a dry and dark place to maintain its stability and quality.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.