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DOTA antibody conjugates have wide application in tissue imaging and tumor diagnostics. DOTA can be conjugated to monoclonal antibodies by attachment of one of the four carboxyl groups as an amide. The remaining three carboxylate anions are available for binding to the yttrium ion. The modified antibody accumulates in the tumour cells, concentrating the effects of the radioactivity of 90Y.

DOTA PEG
  • Bromoacetamido-PEG-DOTA
  • DOTA-(t-Butyl)3-PEG-azide
  • DOTA-PEG-amine
  • DOTA-PEG-azide
  • DOTA-PEG-DBCO
Catalog# Name Structure M.W. Purity Pricing
Bromoacetamido-PEG-DOTA
AP12027Bromoacetamido-PEG5-DOTA787.7≥95% Pricing
DOTA-(t-Butyl)3-PEG-azide
AP11518DOTA-(t-Butyl)3-PEG5-azide861.09≥95% Pricing
DOTA-PEG-amine
AP12200DOTA-PEG5-amine HCl salt666.77≥95% Pricing
DOTA-PEG-azide
AP11517DOTA-PEG5-azide692.77≥95% Pricing
DOTA-PEG-DBCO
AP11147DOTA-PEG5-C6-DBCO982.14≥95% Pricing