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Cationic lipids typically have a positively charged head group followed by a hydrophobic tail of varying composition. In an aqueous environment, these lipids form micelles with positively charged surfaces that complex with DNA. After interacting with nucleic acids, cationic liposomes form aggregated clusters of vesicles. These liposomes act to neutralize charge repulsion between cell membranes and DNA and promote endocytosis, similar to the mechanism of cationic polymers. The positive charge of phospholipids allows cationic liposomes to form complexes with negatively charged nucleic acids (DNA, mRNA, and siRNA) through ionic interactions. These interactions allow cationic liposomes to coagulate and encapsulate various therapeutic and diagnostic agents in their aqueous compartments or in their lipid bilayers.

Cationic Lipid

Cat# Name Structure M.W. Purity Pricing
AP1437614:0 DAP539.90≥95% Pricing
AP14364TAP (14:0)590.40≥95% Pricing
AP1437716:0 DAP596.00≥95% Pricing
AP1436516:0 TAP611.00≥95% Pricing
AP14384GL67615.00≥95% Pricing
AP14378Dimethyldioctadecylammonium bromide631≥95% Pricing
AP14381DODAP (18:1)648.10≥95% Pricing
AP14368DC-6-14661.50≥95% Pricing
AP1436718:1 TAP (DOTAP, MS Salt)663.10≥95% Pricing
AP1436618:0 TAP667.10≥95% Pricing
AP14380DOTMA670.60≥95% Pricing
AP1436912:0 EPC (Cl Salt)686.40≥95% Pricing
AP14379DOTAP698.60≥95% Pricing
AP1437014:0 EPC (Cl Salt)742.50≥95% Pricing
AP14382DORI773.00≥95% Pricing
AP14383DOBAQ782.20≥95% Pricing
AP1437116:0 EPC (Cl Salt)798.60≥95% Pricing
AP1437516:0-18:1 EPC (Cl Salt)824.60≥95% Pricing
AP1437418:1 EPC (Cl Salt)850.70≥95% Pricing
AP1437314:1 EPC (Tf Salt)852.00≥95% Pricing
AP1437218:0 EPC (Cl Salt)854.70≥95% Pricing

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