DBCO-Sulfo-Maleimideimide CAS: 2028281-86-7 is a sulfhydryl (thiol) reactive linker. It contains a maleimide and a DBCO group. The maleimide group reacts specifically and efficiently with thiols and forms a thioether bond. It has been widely used for cysteine-containing peptides/proteins or other thiol-containing biomolecules conjugations. DBCO readily undergoes copper free click chemistry with azide bearing biomolecules and form a stable triazole hinge.
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