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Dibenzocycolctyne – DBCO Linkers can undergo copper free click chemistry Reaction via a strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides. The spontaneously conjugation with azide-modified biomolecules without the need for toxic Cu catalysts makes the DBCO reagents ideal for living cells and organisms study.

DBCO reagents are stable in a broad range of solvents. Functionalized DBCO linkers have broad scope of applications in conjugations, such as cell surface modification, cell imaging, ADC research and tumor targeting delivery, etc.

PEG modified DBCO linkers have improved aqueous solubility. AxisPharm offers PEGylated DBCO with defined spacer length to meet your bioconjugation needs.

Catalog# Name Structure M.W. Purity Pricing
DBCO PEG NHS
AP10862DBCO-C6-NHS ester430.46≥95% Pricing
AP10863DBCO-C4-NHS ester402.41≥95% Pricing
AP10864DBCO-C4-SulfoNHS ester482.46≥95% Pricing
AP10865DBCO-C6-SulfoNHS ester510.52≥95% Pricing
AP10758DBCO-C5-NHS ester416.43≥95% Pricing
AP10302DBCO-CONH-S-S-COONHS Ester565.66≥95% Pricing
AP10301DBCO-COONHS Ester501.53≥95% Pricing
AP11112DBCO-PEG1-NHS ester517.54≥95% Pricing
AP10317DBCO-NH-PEG1-CH2CH2COO NHS Ester561.58≥95% Pricing
AP10030DBCO-PEG3-CH2CONHS591.61≥98% Pricing
AP11113DBCO-PEG4-NHS ester649.7≥95% Pricing
AP11117DBCO-NHCO-PEG4-NHS ester649.7≥95% Pricing
AP11114DBCO-PEG5-NHS ester693.75≥95% Pricing
AP10319DBCO-NH-PEG6-CH2CH2COONHS Ester781.85≥95% Pricing
AP11115DBCO-PEG8-NHS ester825.91≥95% Pricing
AP11116DBCO-PEG12-NHS ester1002.12≥95% Pricing
AP10320DBCO-NH-PEG12-CH2CH2COONHS Ester1046.16≥95% Pricing
AP11118DBCO-PEG2-PFP ester630.57≥95% Pricing
AP11749N-DBCO-N-bis(PEG2-NHS ester)818.83≥95% Pricing
AP11094N-(DBCO-PEG4)-N-Biotin-PEG4-NHS1095.27≥95% Pricing