DBCO-C5-NHS ester, with the CAS number 1393350-27-0, is a chemical compound essential in bioconjugation reactions and organic synthesis. This compound is a derivative of cyclooctyne, a small strained alkyne known for its ability to react with azides to form stable triazole linkages, a process central to DBCO click chemistry. DBCO-C5-NHS ester features a five-carbon linker and an N-hydroxysuccinimide (NHS) ester group. The NHS ester group is particularly adept at reacting with primary amines on biomolecules such as proteins, peptides, or antibodies, enabling specific and efficient labeling.
This compound is frequently utilized in click chemistry, a modular and selective approach for the modification of biomolecules. Click chemistry, especially involving DBCO and azides, represents a major advancement in bioconjugation techniques, offering specificity, rapid reaction times, and high stability. DBCO-C5-NHS ester is a key player in these reactions, providing a reliable method for attaching various biomolecules in a controlled manner. For researchers engaged in these types of bioconjugation processes, understanding the role of DBCO NHS esters can be incredibly beneficial.
In the fields of bioconjugation chemistry and drug discovery research, DBCO-C5-NHS ester stands out as a valuable tool. Its ability to facilitate targeted and efficient conjugation makes it essential for advancing novel therapeutics and diagnostic tools. AxisPharm offers a wide range of DBCO-based compounds, including various DBCO linkers, which are crucial for cutting-edge research in these areas.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.