DBCO-propanamide-thiol CAS:2252493-06-2 is a bioconjugation dbco reagent featuring an azide-reactive DBCO (dibenzocyclooctyne) moiety, a propanamide linker, and a thiol functional group. This unique combination enables efficient and selective coupling with azide-tagged biomolecules in copper-free click chemistry, while providing a reactive thiol group for additional conjugation or functionalization reactions.
Introduction to the Application:
In pharmaceutical research and development, DBCO-propanamide-thiol has gained prominence for its versatile applications in drug delivery, bioimaging, and biomarker discovery. Its ability to form stable, covalent connections with azide-functionalized biomolecules enables the creation of targeted, biocompatible conjugates. This paves the way for the synthesis of innovative therapeutics, including antibody-drug conjugates, nucleic acid-based therapies, and bioorthogonal imaging probes, driving advancements in precision medicine and molecular diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
