Methyltetrazine-PEG6-DBCO is a multifunctional bioconjugate reagent, featuring a methyltetrazine moiety and a DBCO (dibenzocyclooctyne) group, linked by a polyethylene glycol (PEG6) spacer. Methyltetrazine enables rapid, selective click reactions with trans-cyclooctenes, while DBCO allows strain-promoted azide-alkyne cycloaddition (SPAAC) with azides, ensuring biocompatibility and high water solubility.
Introduction to the Application:
In pharmaceutical research and development, Methyltetrazine-PEG6-DBCO serves as a versatile tool for bioorthogonal chemistry, allowing for site-specific labeling and modification of biomolecules, such as proteins, antibodies, and nucleic acids. Its dual-click functionality facilitates the creation of drug conjugates, targeted imaging agents, and biotherapeutics, contributing to advancements in drug delivery, diagnostics, and personalized medicine.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.