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DBCO-amine & DBCO-PEG-amine are functional groups commonly used in drug research and development. These groups are often employed as linkers between drug molecules and other compounds or materials, such as nanoparticles or biomolecules, to enhance the drug’s properties and efficacy.

DBCO, or dibenzocyclooctyne, is a reactive cyclooctyne that forms a covalent bond with azides through a copper-free click reaction known as strain-promoted alkyne-azide cycloaddition (SPAAC). This reaction is highly selective and biocompatible, making DBCO-amine & DBCO-PEG-amine popular choices for bioconjugation and drug delivery applications.

The addition of a PEG (polyethylene glycol) chain to the DBCO-amine molecule allows for improved water solubility and biocompatibility. DBCO-PEG-amine can be used to modify drug molecules, enhance their pharmacokinetics, and reduce toxicity.

DBCO-amine & DBCO-PEG-amine

Cat# Name Structure M.W. Purity Pricing
AP10297DBCO-amine276.33≥95% Pricing
AP13169DBCO-amine TFA salt390.4≥95% Pricing
AP11123DBCO-PEG1-amine391.47≥95% Pricing
AP10298DBCO-C4-amine TFA salt404.38≥95% Pricing
AP11122Sulfo DBCO-amine427.48≥95% Pricing
AP10304DBCO-NH-PEG2-amine435.52≥95% Pricing
AP10755DBCO-C4-PEG2-amine435.52≥95% Pricing
AP10305DBCO-NH-PEG4-amine523.62≥95% Pricing
AP11124DBCO-PEG4-amine523.63≥95% Pricing
AP11128DBCO-C2-PEG4-amine595.69≥95% Pricing
AP11129DBCO-C3-PEG4-amine609.72≥95% Pricing
AP10306DBCO-NH-PEG6-amine611.73≥95% Pricing
AP11125DBCO-PEG6-amine611.74≥95% Pricing
AP11127Sulfo DBCO-PEG4-amine674.77≥95% Pricing
AP13170DBCO-PEG8-amine TFA salt699.8≥95% Pricing
AP11126DBCO-PEG9-amine743.9≥95% Pricing
AP10307DBCO-NH-PEG12-amine876.04≥95% Pricing
AP13173DBCO-PEG23-amine1360.7≥98% Pricing
AP13172DBCO-PEG24-amine TFA salt1404.7≥95% Pricing

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