DBCO-PEG2-DBCO CAS: 2639395-48-3 contains two azide-reactive cyclooctyne functional groups (DBCO) at each end of a PEG chain, which allows for the efficient conjugation of biomolecules through copper-free click chemistry.
In pharmaceutical research and development, DBCO-PEG2-DBCO has been extensively utilized in the development of targeted drug delivery systems. The unique chemical properties of this compound enable the specific attachment of therapeutic agents to targeting molecules, such as antibodies, through the copper-free click reaction. This results in the formation of stable and biocompatible drug conjugates, which can selectively bind to disease-specific targets and deliver the therapeutic agent with high specificity and efficacy.
DBCO-PEG2-DBCO can also be used in the development of imaging agents, such as fluorescent dyes or radionuclides. By attaching these imaging agents to the PEG chain via copper-free click chemistry, highly specific imaging probes can be created for non-invasive detection and visualization of diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.