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DBCO-PEG-DBCO is a type of functional molecule that belongs to the class of click chemistry reagents. It consists of two DBCO (dibenzocyclooctyne) groups linked by a PEG (polyethylene glycol) spacer. DBCO is a cyclooctyne-based compound that has been widely used in bioconjugation reactions due to its high reactivity with azide-functionalized molecules through the copper-free click chemistry method. On the other hand, PEG is a hydrophilic polymer that provides steric hindrance and enhances solubility and stability of the resulting conjugates.

DBCO-PEG-DBCO has been increasingly utilized in drug research and development due to its unique properties. The PEG linker allows for the conjugation of the molecule to a variety of therapeutic agents, such as small molecules, peptides, proteins, and nucleic acids, while the DBCO groups enable the attachment of the conjugate to azide-functionalized substrates, such as surface proteins, lipids, or nanoparticles. This conjugation strategy has been utilized for targeted drug delivery, imaging, and diagnostics.


Cat# Name Structure M.W. Purity Pricing
AP13178DBCO-PEG2-DBCO722.8≥98% Pricing
AP11138DBCO-PEG4-DBCO810.95≥95% Pricing
AP11139DBCO-PEG5-DBCO855≥95% Pricing
AP13179DBCO-PEG6-DBCO 899.1≥98% Pricing
AP13180DBCO-PEG8-DBCO987.2≥98% Pricing
AP11140DBCO-PEG9-DBCO1031.21≥95% Pricing
AP11141DBCO-PEG10-DBCO1075.27≥95% Pricing
AP13181DBCO-PEG12-DBCO1163.4≥98% Pricing
AP11142DBCO-PEG13-DBCO1207.43≥95% Pricing
AP13182DBCO-PEG24-DBCO1433.68≥95% Pricing

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