The DBCO-PEG5-DBCO linker, with the CAS number 2096516-12-8, is a homofunctional DBCO crosslinker recognized for its efficiency in bioconjugation. It is capable of undergoing sequential copper-free click chemistry with azide-tagged biomolecules. This reaction results in the formation of stable triazole linkages, which are spaced out by a hydrophilic PEG spacer. The inclusion of this spacer not only enhances aqueous solubility but also provides rotational flexibility, making it a crucial component in various biomedical applications.
DBCO-PEG8-DBCO stands out as a versatile and valuable tool in pharmaceutical research and development. It offers unique opportunities for the design and optimization of innovative drug delivery systems and biomedical devices. The ability of DBCO to react selectively with azide functional groups through the CuAAC reaction, a cornerstone of DBCO click chemistry, has made it a popular choice in the field of targeted drug delivery. Its potential applications, particularly in cancer therapy, are vast and continually expanding. For researchers focusing on targeted delivery mechanisms, understanding the nuances of DBCO NHS chemistry is also essential.
The functional versatility of DBCO in these contexts underscores its importance in advancing pharmaceutical research. Whether in the form of DBCO-PEG5-DBCO or DBCO-PEG8-DBCO, its role in facilitating effective and targeted drug delivery systems cannot be understated. To explore a wide range of DBCO-based linkers and reagents for your research needs, AxisPharm’s comprehensive collection, including various DBCO linkers, provides high-quality options.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.