Benzyloxy carbonyl-PEG-NHS ester

Benzyloxy carbonyl-PEG-NHS ester is a compound used in pharmaceutical research and development for the modification of biomolecules, such as proteins and peptides, by introducing a functional group. The functional group introduced is the NHS ester, which reacts with amino groups present in the biomolecules, allowing for the attachment of PEG (polyethylene glycol) chains. PEGylation of biomolecules has been shown to improve their pharmacokinetic properties, such as increasing their half-life in the bloodstream and reducing their immunogenicity. This makes PEGylation an important strategy in the development of biopharmaceuticals. Benzyloxy carbonyl-PEG-NHS ester is a useful tool for introducing PEG chains onto biomolecules, as it provides a stable and reactive intermediate that can be easily handled and stored prior to use.