3-(2-bromoacetamido)propanoic acid NHS ester linker contains a bromide group and an NHS ester. The PEG spacer increases the aqueous solubility of the resulting compound. The bromoacetamide is a very good leaving group for nucleophilic substitution reactions and is widely used for cysteine thiol labeling and capping. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.