Propargyl-PEG4-NHS ester is a PEG Linker with a terminal alkyne group and an active NHS ester group on the ends. While the reactive NHS ester end can readily conjugate with an amine groupfrom peptides, antibodies, amine coated surfaces etc, the propargyl group readily reacts with azide-bearing compounds or biomolecules through click chemistry to form a stable triazole linkage. The increasing aqueous solubility derived from PEG spacer makes such linker an ideal conjugation linkers for biological applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.