Amine-PEG (PEG Amine) Overview
Amine-PEG (PEG Amine) offers a flexible reagent with a
PEG chain and a terminal
amine group. The
amine easily reacts with carboxyls, NHS esters, and other reactive groups, while the
PEG chain boosts solubility and biocompatibility. It works well in
bioconjugation,
drug delivery, and
surface modification.
Key Features:
- Amine Group: Quickly reacts with carboxyls and other groups for efficient linking.
- PEG Chain: Improves solubility, reduces immune responses, and increases stability.
- Biocompatibility: PEGylation minimizes protein adsorption and enhances tissue compatibility.
Applications:
- Bioconjugation: Links proteins, peptides, and molecules through amine-coupling.
- Drug Delivery: Increases solubility and circulation of therapeutic agents.
- Surface Modification: Coats surfaces, creating hydrophilic, biocompatible layers on devices or particles.
Advantages:
- High Reactivity: The amine ensures strong, stable connections.
- Enhanced Solubility: PEG backbone boosts water solubility and prevents aggregation.
- Versatile Applications: Ideal for drug development, bioconjugation, and material science.
Amine-PEG (PEG Amine) fits perfectly for
bioconjugation,
therapeutics, and
surface engineering, providing a simple, reliable way for linking molecules and modifying surfaces.