Showing the single result

Show sidebar

DOTA-PEG-amine is a versatile molecule widely used in drug research and development. It belongs to the family of macrocyclic chelators, containing the functional groups of carboxylic acid, amine, and ether. DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) is a macrocyclic chelator that can form stable complexes with metal ions, while PEG (polyethylene glycol) is a polymer that can improve solubility, bioavailability, and pharmacokinetics of drugs. The addition of an amine group in DOTA-PEG-amine further enhances its reactivity and versatility for various applications.

In drug research and development, DOTA-PEG-amine is commonly used as a linker to attach metal ions or drugs to targeting molecules, such as antibodies, peptides, or proteins. This enables the specific delivery of drugs to disease sites, such as cancer cells, while reducing off-target effects and toxicity. Moreover, DOTA-PEG-amine can also be labeled with radioactive isotopes for imaging and diagnosis, such as PET (positron emission tomography) and SPECT (single-photon emission computed tomography) scans.

DOTA-PEG-amine is a valuable tool in drug research and development, with its functional groups providing the necessary reactivity and versatility for various applications. Its classification as a macrocyclic chelator with additional PEG and amine groups further enhances its potential for drug delivery, imaging, and diagnosis.


Cat# Name Structure M.W. Purity Pricing
AP12200DOTA-PEG5-amine HCl salt666.77≥95% Pricing

Bulk Inquiry