Amino-PEG3-sulfonic acid HCl salt contains an amine group and a sulfonic acid moiety. The amine group readily reacts with carboxylic acids, activated NHS, PFP, TFP esters to form amide bond or with other carbonyl groups, such as ketone and aldehyde to form C-N bond by reductive amination. The sulfonic acid can undergoes esterification, halogenation replacement and hydrolysis under basic conditions. The combination of hydrophilic PEG space and strong sulfonic acid great increase the solubility of the compound in biological media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.