Thiol-PEG-amine(Amino-PEG-Thiol) is a class of molecules that are widely used in pharmaceutical research and development. Thiol refers to the functional group containing sulfur, while PEG stands for polyethylene glycol, and amine refers to the nitrogen-containing functional group. Thiol-PEG-amine is a type of polyethylene glycol-based molecule that is highly flexible, biocompatible, and water-soluble. It has been widely used in the design of drug delivery systems and in the modification of therapeutic proteins. The thiol group in Thiol-PEG-amine allows for the attachment of other functional groups, such as carboxylic acids, aldehydes, and amines, which can be used for various applications. The introduction of functional groups allows for the customization of Thiol-PEG-amine, making it an essential tool for pharmaceutical research and development.