Biotin tetrazine PEG(Biotin-peg-tetrazine) is a class of molecules that belong to the family of PEGylated compounds. These compounds contain a biotin group, a tetrazine group, and a polyethylene glycol (PEG) chain. Biotin tetrazine PEG molecules are widely used in drug research and development due to their unique functional groups and properties.
The biotin group in it is a vitamin H derivative that is commonly used as a targeting moiety for specific biomolecules. Biotin can bind to avidin or streptavidin proteins, which are commonly used in immunoassays and protein detection assays. The tetrazine group is a highly reactive diene that can undergo a bioorthogonal click reaction with trans-cyclooctene (TCO) groups. This reaction can be used for the selective labeling of biomolecules in complex biological systems. The PEG chain in biotin tetrazine PEG provides steric stability, solubility, and biocompatibility.
It has shown great potential in drug research and development due to its unique functional groups. It can be used for targeted drug delivery, imaging, and diagnosis. Biotin tetrazine PEG can be conjugated to drugs or imaging agents and specifically delivered to target cells or tissues by binding to biotin receptors. The tetrazine group can be used for bioorthogonal click reactions to selectively label proteins or biomolecules in complex biological systems, allowing for the identification and quantification of specific targets.
It is a versatile class of molecules that has a wide range of applications in drug research and development. Its unique functional groups provide specific targeting and labeling capabilities, making it a promising tool for the development of targeted therapies, imaging agents, and diagnostic tools.
Biotin Tetrazine PEG