Tetrazine-PEG4-biotin is a high-performance bifunctional bioconjugation reagent, specifically designed to streamline pharmaceutical research and development processes. It features three distinct functional groups: a tetrazine moiety, a PEG4 linker, and a biotin unit.
The tetrazine group enables rapid and selective bioorthogonal click chemistry reactions, such as inverse-electron-demand Diels-Alder reactions, with strained alkenes and alkynes. This property makes it an invaluable tool for labeling and tracking target molecules in complex biological systems with minimal interference.
The PEG4 spacer, a hydrophilic polyethylene glycol linker, enhances water solubility and reduces steric hindrance, allowing for improved accessibility and reactivity in bioconjugation reactions. Additionally, the PEG4 linker minimizes non-specific binding, thus ensuring high signal-to-noise ratios in analytical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.