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PEG NHS ester linkers have been widely usded for crosslinking or labeling peptides and proteins. They readily react with primary amine groups at the N-terminus of polypeptide chains and lysine amino groups. These primary amines exist predominantly on the outside surfaces of protein and are readily accessible to NHS ester for bioconjugations. In addition, these primary amines are nucleophilic enough to react with PEG NHS esters for protein crosslinking and labeling.

The functional groups on the other end of the linkers provide protein scientist opportunities for further conjugation with other biomolecules or drug targets.

Incorporating a PEG spacer can dramatically improve the solubility of the linker and make them ideal for ADC conjugations as most of the process take place in aqueous media.

AxisPharm maintain a large collection of high quality PEG NHS ester linkers for our clients to select. For custom synthesis of ADC linkers, please contact us. 

Catalog# Name Structure M.W. Purity Pricing
PEG NHS Ester
AP10731endo-BCN-PEG4-PFP ester607.56≥95% Buy
AP10584Endo-BCN-PEG4-NHS ester538.59≥95% Buy
AP10548endo-BCN-NHS291.3≥95% Buy
AP117002-(Azido-PEG3-amido)-1,3-bis(NHS Ester)658.62≥95% Buy
AP120163-(2-bromoacetamido)propanoic acid NHS ester307.1≥95% Buy
AP113433-(m-PEG8-ethoxycarbonyl)propanoic-NHS ester581.61≥95% Buy
AP119485-Maleimido-pentanoic NHS ester294.26≥95% Buy
AP114916-Maleimidocaproic acid PFP ester377.27≥95% Buy
AP11826Acid-PEG13-NHS ester787.85≥95% Buy
AP11827Acid-PEG25-NHS ester1316.49≥95% Buy
AP11823Acid-PEG3-NHS ester347.32≥95% Buy
AP11656Acid-PEG3-PFP ester416.3≥95% Buy
AP11824Acid-PEG5-NHS ester435.43≥95% Buy
AP11825Acid-PEG9-NHS ester611.64≥95% Buy
AP12246Ald-Ph-PEG12-TFP ester897.91≥95% Buy
AP12243Ald-Ph-PEG2-NHS406.39≥95% Buy
AP12245Ald-Ph-PEG24-NHS ester1375.56≥95% Buy
AP12247Ald-Ph-PEG24-TFP ester1426.54≥95% Buy
AP12244Ald-Ph-PEG4-NHS ester494.5≥95% Buy
AP11412alpha-lipoic acid-NHS303.39≥95% Buy
AP11952ANB-NOS Crosslinker305.21≥95% Buy
AP11528Azido-PEG1-CH2CO2-NHS242.19≥95% Buy
AP11523Azido-PEG1-NHS ester256.22≥95% Buy
AP11535Azido-PEG1-PFP ester325.2≥95% Buy
AP11527Azido-PEG10-NHS ester652.7≥95% Buy
AP11529Azido-PEG2-CH2CO2-NHS286.24≥95% Buy
AP11520Azido-PEG2-CH2CO2H189.17≥95% Buy
AP11524Azido-PEG2-NHS ester300.27≥95% Buy
AP11536Azido-PEG2-PFP ester369.25≥95% Buy
AP11534Azido-PEG3-aminoacetic acid-NHS ester373.37≥95% Buy
AP11530Azido-PEG3-CH2CO2-NHS330.3≥95% Buy
AP11537Azido-PEG3-PFP ester413.3≥95% Buy
AP11593Azido-PEG4-4-nitrophenyl carbonate384.35≥95% Buy
AP11531Azido-PEG4-CH2CO2-NHS374.35≥95% Buy
AP11538Azido-PEG4-PFP ester457.35≥95% Buy
AP11532Azido-PEG5-CH2CO2-NHS418.4≥95% Buy
AP11542Azido-PEG5-CH2CO2-PFP487.38≥95% Buy
AP11525Azido-PEG5-NHS ester432.43≥95% Buy
AP11539Azido-PEG5-PFP ester501.41≥95% Buy
AP11540Azido-PEG6-PFP ester545.46≥95% Buy
AP11533Azido-PEG8-CH2CO2-NHS550.56≥95% Buy
AP11543Azido-PEG8-CH2CO2-PFP619.54≥95% Buy
AP11541Azido-PEG8-PFP ester633.57≥95% Buy
AP11526Azido-PEG9-NHS ester608.64≥95% Buy
AP11522Azidoacetic acid NHS ester198.14≥95% Buy
AP11947Azidobutyric acid NHS ester226.19≥95% Buy
AP11157Azidoethyl-SS-propionic NHS ester304.34≥95% Buy
AP11198BCN-PEG3-VC-PFP Ester819.82≥95% Buy
AP11672Benzyloxy carbonyl-PEG3-NHS ester437.45≥95% Buy
AP11183Biotin-bisamido-SS-NHS575.71≥95% Buy
AP11075Biotin-EDA-PEG4-PFP728.73≥95% Buy
AP11037Biotin-PEG12-TFP ester992.08≥95% Buy
AP11038Biotin-PEG24-TFP ester1520.72≥95% Buy
AP11039Biotin-PEG36-PFP ester2067.35≥95% Buy
AP11036Biotin-PEG4-TFP ester639.66≥95% Buy
AP11040Biotin-PFP ester410.36≥95% Buy
AP11497Bis-Mal-Lysine-PEG4-TFP ester843.78≥95% Buy
AP11513Bis-PE21 NHS ester1237.35≥95% Buy
AP11502Bis-PEG1-NHS ester356.29≥95% Buy
AP11970Bis-PEG1-PFP ester494.24≥95% Buy
AP11509Bis-PEG10-NHS ester752.76≥95% Buy
AP11510Bis-PEG11-NHS ester796.82≥95% Buy
AP11511Bis-PEG13-NHS ester884.92≥95% Buy
AP11976Bis-PEG13-PFP ester1022.88≥95% Buy
AP11512Bis-PEG17-NHS ester1061.14≥95% Buy
AP11971Bis-PEG2-PFP ester538.29≥95% Buy
AP11514Bis-PEG25-NHS ester1413.56≥95% Buy
AP11977Bis-PEG25-TFP ester1515.53≥95% Buy
AP11503Bis-PEG3-NHS ester444.39≥95% Buy
AP11504Bis-PEG4-NHS ester488.45≥95% Buy
AP11972Bis-PEG4-PFP ester626.4≥95% Buy
AP11505Bis-PEG5-NHS ester532.5≥95% Buy
AP11973Bis-PEG5-PFP ester670.45≥95% Buy
AP11506Bis-PEG6-NHS ester576.55≥95% Buy
AP11507Bis-PEG7-NHS ester620.61≥95% Buy
AP11974Bis-PEG7-PFP ester758.56≥95% Buy
AP11508Bis-PEG9-NHS ester708.71≥95% Buy
AP11975Bis-PEG9-PFP ester846.67≥95% Buy
AP12017Bromoacetamido-PEG2-NHS ester395.21≥95% Buy
AP11956BS2G Crosslinker530.34≥95% Buy
AP11957BS3 Crosslinker572.42≥95% Buy
AP12029Chloroacetamido-PEG4-NHS ester438.86≥95% Buy
AP11117DBCO-NHCO-PEG4-NHS ester649.7≥95% Buy
AP11112DBCO-PEG1-NHS ester517.54≥95% Buy
AP11116DBCO-PEG12-NHS ester1002.12≥95% Buy
AP11118DBCO-PEG2-PFP ester630.57≥95% Buy
AP11113DBCO-PEG4-NHS ester649.7≥95% Buy
AP11119DBCO-PEG4-PFP ester718.67≥95% Buy
AP11114DBCO-PEG5-NHS ester693.75≥95% Buy
AP11115DBCO-PEG8-NHS ester825.91≥95% Buy
AP12231DNP-PEG12-NHS ester880.9≥95% Buy
AP12230DNP-PEG4-NHS ester528.47≥95% Buy
AP11954DSP Crosslinker404.41≥95% Buy
AP11959DSS Crosslinker368.34≥95% Buy
AP11516EGS Crosslinker456.36≥95% Buy
AP12352endo-BCN-PEG12-NHS ester891.02≥95% Buy
AP12349endo-BCN-PEG2-NHS ester450.49≥95% Buy
AP12353endo-BCN-PEG2-PFP ester519.47≥95% Buy
AP12350endo-BCN-PEG3-NHS ester494.54≥95% Buy
AP12354endo-BCN-PEG4-PFP ester607.57≥95% Buy