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Thiol Reactive Linkers are used in ADC conjugation to target thiol group on biomolecules. Maleimide, acrylamide or vinyl sulfone are some of the most useful thiol reactive agents for bioconjugation. The maleimide linkers allow selective labeling of sulfhydryl groups such as cysteine residues in proteins and pepties, and oligonucleotides. Functionalized maleimide linkers with PEG spacer of different length offers researchers flexibility to fine tune their conjugation applications.

Catalog# Name Structure M.W. Purity Pricing
Thiol Reactive Linkers Thiol Labeling Probes
AP10062Mal-amide-PEG2-oxyamine315.32≥95% Pricing
AP10061Mal-amide-PEG3-oxyamine359.37≥95% Pricing
AP10060Mal-amide-PEG2-oxyamineBoc415.44≥95% Pricing
AP10059Mal-amide-PEG3-oxyamineBoc459.49≥95% Pricing
AP10659N-(2-(bicyclo[2.2.1]hept-5-ene-2-carboxamido)ethyl)pyrene-1-carboxamide408.5≥95% Pricing
AP10619N-Bicyclo[2.2.1]hept-5-en-2-ylmethyl-4-pyren-1-yl-butanamide393.52≥95% Pricing
AP10316DBCO-NH-PEG12-Mal1027.16≥95% Pricing
AP10158m-PEG2-Mal199.21≥95% Pricing
AP10157m-PEG3-Mal243.26≥95% Pricing
AP10186m-PEG6-NH-Mal446.49≥95% Pricing
AP10187m-PEG8-NH-Mal534.6≥95% Pricing
AP11515Di(N-succinimidyl)adipate340.29≥95% Pricing
AP11629tert-butyl 2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethylcarbamate240.26≥95% Pricing
AP116306-Mal-C6-Boc-Amine296.37≥95% Pricing
AP10164Mal-PEG2-acid257.24≥95% Pricing
AP10224Mal-PEG4-acid345.35≥95% Pricing
AP10225Mal-PEG6-acid433.45≥95% Pricing
AP10226Mal-PEG8-acid521.56≥95% Pricing
AP10162Mal-peg2-t-butyl ester313.35≥95% Pricing
AP10050Mal-PEG3-amine272.3≥95% Pricing
AP10063Mal-amide-PEG3-CH2 NHS ester455.42≥95% Pricing
AP10227Mal-NH-PEG4-CH2CH2COONHS513.5≥95% Pricing
AP10651N-(6-Aminohexyl)maleimide TFA salt310.27≥95% Pricing
AP10146Mal NHS ester266.21≥95% Pricing
AP101553,4-Dibromo-Mal-PEG2-Boc-Amine486.16≥95% Pricing