Thiol Reactive Linkers Thiol Labeling Probes

Thiol Reactive Linkers are used in ADC conjugation to target thiol group on biomolecules. Maleimide, acrylamide or vinyl sulfone are some of the most useful thiol reactive agents for bioconjugation. The maleimide linkers allow selective labeling of sulfhydryl groups such as cysteine residues in proteins and pepties, and oligonucleotides. Functionalized maleimide linkers with PEG spacer of different length offers researchers flexibility to fine tune their conjugation applications.