Lipoamido-PEG4-acid contains a lipoamideand a terminal carboxylic acid. The lipoic acid is a co-factor that is used in biological systems such as the citric acid cycle. The carboxylic acid can react with primary amines in the presence of coupling reagents, such as EDC, DCC and HATU form stable amide bonds. The hydrophilic PEG spacer can increase the compound’s solubility in aqueous environments.
AxisPharm offers 4000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.